From: Plasma fractalkine is a sustained marker of disease severity and outcome in sepsis patients
CAP | No CAP | P | |
---|---|---|---|
n = 271 | n = 73 | ||
Demographics | |||
Age, years, mean (SD) | 59.7 (16.7) | 58.8 (17.2) | 0.70 |
Gender, male, n (%) | 155 (57.2) | 40 (54.8) | 0.79 |
Race, white, n (%) | 236 (87.1) | 57 (78.1) | 0.04 |
Body mass index, kg/m2, mean (SD) | 24.9 (6.0) | 26.4 (9.4) | 0.21 |
Charlson score, median (IQR) | 4 (2–6) | 3 (2–5) | 0.07 |
Severity of disease in first 24 hours | |||
APACHE IV score, median (IQR) | 79 (62–101) | 68 (52–99) | 0.07 |
SOFA score, median (IQR)a | 7 (4–9) | 6 (3–7) | 0.01 |
Shock, n (%) | 71 (26.2) | 10 (13.7) | 0.03 |
Mechanical ventilation, n (%) | 203 (74.9) | 57 (78.1) | 0.66 |
Renal replacement therapy, n (%) | 19 (7) | 4 (5.5) | 0.78 |
Outcome | |||
ICU length of stay, days, median (IQR) | 5 (2–11) | 2 (1–4) | <0.0001 |
ICU mortality, n (%) | 53 (19.6) | 9 (12.3) | 0.18 |
30-day mortality, n (%) | 73 (26.9) | 16 (21.9) | 0.37 |
90-day mortality, n (%) | 92 (33.9) | 19 (26) | 0.16 |
1-year mortality, n (%) | 121 (44.6) | 30 (41.1) | 0.50 |