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Fig. 9 | Critical Care

Fig. 9

From: Milk fat globule epidermal growth factor-factor 8-derived peptide attenuates organ injury and improves survival in sepsis

Fig. 9

MFG-E8-derived short peptide 6 (MSP68) improves the survival in cecal ligation and puncture (CLP)-induced sepsis. Mice were subjected to CLP followed by a single subcutaneous injection of 0.5 mg/kg antibiotic. At 2 h after CLP, mice were injected with normal saline as vehicle (n = 23) or 1 mg/kg of MSP68 (n = 24) through the jugular vein and survival was recorded for 10 days. The survival rate was estimated by the Kaplan–Meier method and compared using the log-rank test; *P = 0.05 versus vehicle

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Critical Care

ISSN: 1364-8535