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Table 1 Patient characteristics of all patients and compared between patients with and patients without acute kidney injury

From: Fluid balance and mortality in critically ill patients with acute kidney injury: a multicenter prospective epidemiological study

Characteristics All (n = 2526) AKI (n = 1172) Non-AKI (n = 1354) P value
Age (yr) 64 (52–77) 67 (54–78) 63 (50–75) <0.001
Male sex 1578 (62.5) 742 (63.3) 836 (61.7) 0.434
APACHE II score 14 (10–20) 17 (12–23) 13 (9–17) <0.001
SAPS II score 34 (26–46) 40 (31–52) 31 (24–39) <0.001
SOFA score 6 (4–9) 7 (5–10) 5 (3–7) <0.001
Vasoactive therapy 1009 (40.0) 576 (49.1) 433 (32.0) <0.001
Mechanical ventilation 1702 (67.4) 818 (69.8) 884 (65.3) 0.017
Baseline creatinine (μmol/L) 81.9 (69.0–96.0) 84.9 (73.0–97.0) 79.8 (66.8–95.0) <0.001
Sepsis 808 (32.0) 512 (43.7) 296 (21.9) <0.001
Fluid balance within 24 h (L) 0.57 (−0.19 to 1.43) 0.64 (−0.20 to 1.70) 0.53 (−0.18 to 1.30) <0.001
Fluid balance within 48 h (L) 0.88 (−0.37 to 2.30) 1.06 (−0.38 to 2.82) 0.73 (−0.37 to 1.91) <0.001
Fluid balance within 72 h (L) 1.12 (−0.48 to 2.86) 1.40 (−0.49 to 3.54) 0.91 (−0.48 to 2.44) 0.001
Use of diuretics (%) 1500 (59.4) 872 (74.4) 628 (46.4) <0.001
28-day mortality 438 (17.3) 301 (25.7) 137 (10.1) <0.001
Length of ICU stay (days) 6 (4–11) 7 (5–14) 5 (4–9) <0.001
  1. Data are expressed as median (interquartile range) or number (percent)
  2. AKI acute kidney injury, ICU intensive care unit, APACHE II Acute Physiology and Chronic Health Evaluation II, SAPS II Simplified Acute Physiology Score II, SOFA Sequential Organ Failure Assessment