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Table 1 Patient characteristics of all patients and compared between patients with and patients without acute kidney injury

From: Fluid balance and mortality in critically ill patients with acute kidney injury: a multicenter prospective epidemiological study

Characteristics

All (n = 2526)

AKI (n = 1172)

Non-AKI (n = 1354)

P value

Age (yr)

64 (52–77)

67 (54–78)

63 (50–75)

<0.001

Male sex

1578 (62.5)

742 (63.3)

836 (61.7)

0.434

APACHE II score

14 (10–20)

17 (12–23)

13 (9–17)

<0.001

SAPS II score

34 (26–46)

40 (31–52)

31 (24–39)

<0.001

SOFA score

6 (4–9)

7 (5–10)

5 (3–7)

<0.001

Vasoactive therapy

1009 (40.0)

576 (49.1)

433 (32.0)

<0.001

Mechanical ventilation

1702 (67.4)

818 (69.8)

884 (65.3)

0.017

Baseline creatinine (μmol/L)

81.9 (69.0–96.0)

84.9 (73.0–97.0)

79.8 (66.8–95.0)

<0.001

Sepsis

808 (32.0)

512 (43.7)

296 (21.9)

<0.001

Fluid balance within 24 h (L)

0.57 (−0.19 to 1.43)

0.64 (−0.20 to 1.70)

0.53 (−0.18 to 1.30)

<0.001

Fluid balance within 48 h (L)

0.88 (−0.37 to 2.30)

1.06 (−0.38 to 2.82)

0.73 (−0.37 to 1.91)

<0.001

Fluid balance within 72 h (L)

1.12 (−0.48 to 2.86)

1.40 (−0.49 to 3.54)

0.91 (−0.48 to 2.44)

0.001

Use of diuretics (%)

1500 (59.4)

872 (74.4)

628 (46.4)

<0.001

28-day mortality

438 (17.3)

301 (25.7)

137 (10.1)

<0.001

Length of ICU stay (days)

6 (4–11)

7 (5–14)

5 (4–9)

<0.001

  1. Data are expressed as median (interquartile range) or number (percent)
  2. AKI acute kidney injury, ICU intensive care unit, APACHE II Acute Physiology and Chronic Health Evaluation II, SAPS II Simplified Acute Physiology Score II, SOFA Sequential Organ Failure Assessment