Prognostic significance of the angiopoietin-2/angiopoietin-1 and angiopoietin-1/Tie-2 ratios for early sepsis in an emergency department

Table 3 AUCs for predicting 28-day mortality in patients with early sepsis

	Variable	AUC	Standard error	p value	95 % CI
	Variable	AUC	Standard error	p value	Lower limit	Upper limit
28-day mortality	Ang-1	0.778	0.024	0	0.732	0.824
	Ang-2	0.794	0.018	0	0.750	0.837
	Tie-2	0.803	0.024	0	0.756	0.849
	Ang-2/Ang-1	0.845	0.018	0	0.810	0.880
	Ang-1/Tie-2	0.808	0.023	0	0.763	0.853
	PCT	0.732	0.024	0	0.685	0.780
	MEDS score	0.826	0.021	0	0.785	0.866
	Ang-2/Ang-1+MEDS score	0.857	0.018	0	0.821	0.893
	Ang-1/Tie-2+MEDS score	0.844	0.020	0	0.805	0.883
	PCT+MEDS score	0.829	0.020	0	0.790	0.869
	Ang-2/Ang-1+PCT+MEDS score	0.900	0.017	0	0.866	0.934
	Ang-1/Tie-2+PCT+MEDS score	0.894	0.016	0	0.862	0.926
	Ang-2/Ang-1+Ang-1/Tie-2+PCT+MEDS score	0.925	0.013	0	0.898	0.951

Abbreviations: Ang angiopoietin, AUC area under the receiver operating characteristic curve, CI confidence interval, MEDS Mortality in Emergency Department Sepsis, PCT procalcitonin, Tie-2 tyrosine kinase with immunoglobulin-like loop epidermal growth factor homology domain 2

ISSN: 1364-8535