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Table 3 Adjusted associations between subgroups and hospital mortality

From: Associations of arterial carbon dioxide and arterial oxygen concentrations with hospital mortality after resuscitation from cardiac arrest

Group comparison   Odds ratio (95 % CI) P value
PaCO2 groups   
 Hypocapnia vs. normocapnia 1.39 (1.18–1.63)a <0.001
 Hypercapnia vs. normocapnia 1.10 (0.95–1.27)a 0.20
 Hypercapnia vs. hypocapnia 0.79 (0.67–0.94)a <0.01
PaO2 groups   
 Hypoxia vs. normoxia 1.34 (1.08–1.66)b <0.01
 Hyperoxia vs. normoxia 1.13 (0.81–1.57)b 0.46
 Hyperoxia vs. hypoxia 0.85 (0.58–1.24)b 0.39
Alternative PaO2 categoriesc   
 55-80 vs. >300 mmHg 1.06 (0.76–1.50)b 0.72
 80-102 vs. >300 mmHg 0.90 (0.64–1.27)b 0.55
 102-300 vs. >300 mmHg 0.79 (0.56–1.11)b 0.17
  1. Hypocapnia = PaCO2 < 35 mmHg; normocapnia = PaCO2 35–45 mmHg; hypercapnia = PaCO2 > 45 mmHg
  2. Hypoxia = PaO2 < 60 mmHg; normoxia = PaO2 60–300 mmHg; hyperoxia = PaO2 > 300 mmHg
  3. aMultivariable analysis adjusted for age, lowest glucose, AP4-adj and PaO2 (splines)
  4. bMultivariable analysis adjusted for age, lowest glucose, AP4-adj and PaCO2 (splines)
  5. cStratification based on thresholds from ARDSnet oxygenation target (55–80 mmHg), upper threshold of median cohort quintile (102 mmHg), and threshold from previous studies (300 mmHg)