Discordant identification of pediatric severe sepsis by research and clinical definitions in the SPROUT international point prevalence study

Table 5 Multivariable logistic regression model of the association of severe sepsis definition with PICU mortality

Variable	Adjusted OR^a	95 % confidence interval	p value
Severe sepsis definition
Both criteria	Reference
Physician diagnosis, only	0.64	0.37–1.11	0.12
Consensus criteria, only	0.73	0.48–1.12	0.15
Age, yr	0.99	0.95–1.02	0.45
PIM-3 score	1.04	1.03–1.06	<0.001
Comorbid conditions
None	Reference
1 comorbid condition	1.11	0.62–2.01	0.72
≥2 comorbid conditions	1.78	1.07–2.99	0.03
Developed region^b	0.63	0.37–1.06	0.08

OR odds ratio, PIM-3 Pediatric Index of Mortality-3
^aOdds ratios are adjusted for all of the variables listed
^bSites included as “developed regions” were located in North America, Australia/New Zealand, and Europe

ISSN: 1364-8535