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Table 5 Multivariable logistic regression model of the association of severe sepsis definition with PICU mortality

From: Discordant identification of pediatric severe sepsis by research and clinical definitions in the SPROUT international point prevalence study

Variable Adjusted ORa 95 % confidence interval p value
Severe sepsis definition    
 Both criteria Reference   
 Physician diagnosis, only 0.64 0.37–1.11 0.12
 Consensus criteria, only 0.73 0.48–1.12 0.15
Age, yr 0.99 0.95–1.02 0.45
PIM-3 score 1.04 1.03–1.06 <0.001
Comorbid conditions    
 None Reference   
 1 comorbid condition 1.11 0.62–2.01 0.72
 ≥2 comorbid conditions 1.78 1.07–2.99 0.03
Developed regionb 0.63 0.37–1.06 0.08
  1. OR odds ratio, PIM-3 Pediatric Index of Mortality-3
  2. aOdds ratios are adjusted for all of the variables listed
  3. bSites included as “developed regions” were located in North America, Australia/New Zealand, and Europe