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Table 2 Baseline characteristics of patients with suspected infection with and without acute organ dysfunction codes (2005–2013)

From: Improving documentation and coding for acute organ dysfunction biases estimates of changing sepsis severity and burden: a retrospective study

Patient characteristics

Any organ dysfunction code

No organ dysfunction code

(n = 57,273)

(n = 134,422)

Median age (interquartile range)

65 (53, 76)

59 (45, 72)

Male sex

32,779 (57.2)

67,041 (49.9)

White race

44,413 (77.6)

102,539 (76.3)

Comorbidities

 Cancer (solid, metastatic, lymphoma)

12,284 (21.5)

31,032 (23.1)

 Diabetes (with and without complications)

9947 (17.4)

24,786 (18.4)

 Congestive heart failure

13,647 (23.8)

15,352 (11.4)

 Liver disease

4484 (7.8)

6896 (5.1)

 Lung disease

8374 (14.6)

21,726 (16.2)

 Renal disease

10,555 (18.4)

14,350 (10.7)

Acute organ dysfunction codes:

 Hypotension/shock

9948 (17.4)

_

 Respiratory

16,552 (28.9)

_

 Renal

34,500 (60.2)

_

 Acidosis

8315 (14.5)

_

 Hepatic

2875 (5.0)

_

 Thrombocytopenia

9426 (16.5)

_

 Coagulopathy

2878 (5.0)

_

 Median number of organ dysfunction codes

1 (1, 2)

_

Objective clinical markers of organ dysfunction:

 Hypotension/shock

24,181 (42.2)

17,887 (13.3)

 Respiratory

18,532 (32.4)

7355 (5.5)

 Renal

19,094 (33.3)

3352 (2.5)

 Acidosis

10,236 (17.9)

2093 (1.6)

 Hepatic

6010 (10.5)

2526 (1.9)

 Thrombocytopenia

9703 (16.9)

7980 (5.9)

 Coagulopathy

5871 (10.3)

3147 (2.3)

 Median number of objective dysfunctional organs

1 (0, 2)

0 (0, 0)

Median hospital length of stay (interquartile range)

11 (6, 20)

6 (4, 11)

Hospital mortality

9265 (16.2)

2775 (2.1)