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Table 4 Factors associated with ICU mortality in a cohort of 157 patients admitted for bacterial meningitis

From: Rifampin use in acute community-acquired meningitis in intensive care units: the French retrospective cohort ACAM-ICU study

Variable Odds ratio (95 % CI) p Value
Pulmonary failure 67.7 (3.7–1225.7) 0.004
Renal failure 12.6 (2.2–73.1) 0.005
Cardiovascular failure 9.8 (1.7–57.6) 0.012
Pneumococcal infection 9.0 (1.1–74.8) 0.042
Early antibiotic administration (<2 h) 0.3 (0.0–1.6) 0.155
Hematologic failure 3.6 (0.6–20.6) 0.156
Corticosteroid administration 4.1 (0.5–36.2) 0.200
Age (>75 yr)   NS
Immunosuppression   NS
Female sex   NS
Early treatment with rifampin (<24 h)   NS
  1. Incomplete observations were excluded from the logistic analysis. The presented final model had 134 observations entered and yielded the highest likelihood ratio. Nagelkerke’s R 2 was 0.69. The 11 presented variables were those included in the final logistic model
  2. p Values <0.2 are detailed. p Values <0.05 were considered significant (bold)