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Table 4 Predictive value of the cuff leak test and laryngeal ultrasonography for postextubation stridor, laryngeal edema, and reintubation

From: Postextubation laryngeal edema and stridor resulting in respiratory failure in critically ill adult patients: updated review

Author Year Predefined cutoff value Outcome Sensitivity Specificity PPV NPV
Cuff leak test   Volume, ml Percentage of tidal volume      
Miller and Cole [22] 1996 110   Stridor 0.67 (0.51–0.82) 0.99 0.80 0.98
Jaber et al. [25] 2003 130 12 Stridor 0.85 (0.65–0.99) 0.95 (0.91–0.99) 0.69 0.98
De Bast et al. [2] 2002   15.5 Reintubation 0.75 0.72 0.25 0.96
Sandhu et al. [21] 2000   10.0 Stridor or reintubation 0.54 0.96 0.64 0.94
Wang et al. [19] 2007 88   Stridor 0.60 0.89 0.55 0.91
Maury et al. [20] 2004 0   Stridor 1.00 0.80 0.15 1.00
Chung et al. [13] 2006 140   Laryngeal edema 0.89 0.90 0.84 0.93
Engoren [34] 1999 110   Stridor 0.00 0.96 0.00 0.99
Kriner et al. [18] 2005 110   Stridor 0.50 0.84 0.12 0.97
Cheng et al. [16] 2006   18.0 Stridor 0.85 0.72 0.21 0.98
Mikaeili et al. [28] 2014 110   Stridor 0.25 0.84 0.14 0.91
130 0.25 0.81 0.13 0.91
249 0.75 0.59 0.17 0.96
Gros et al. [27] 2012 130   Stridor 0.86 (0.42–1.00) 0.76 (0.67–0.84) 0.21 (0.08–0.40) 0.99 (0.93–1.00)
Sutherasan et al. [15] 2013 110   Laryngeal edema 0.80 0.82 0.46 0.96
Ultrasonography   ACWD, mm      
Sutherasan et al. [15] 2013 1.6 Laryngeal edema 0.71 0.70 0.32 0.92
Mikaeili et al. [28] 2014 0.85 Stridor 0.50 0.57 0.11 0.91
  1. 95 % confidence intervals are provided if available
  2. Adapted from Wittekamp et al. [4]
  3. PPV positive predictive value, NPV negative predictive value, ACWD air column width difference
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