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Table 4 Performance of SpO2/FiO2 and ultrasound interstitial syndrome (UIS) as a marker for with acute respiratory distress syndrome (ARDS) criteria when SpO2 ≤ 97 %

From: Pulmonary ultrasound and pulse oximetry versus chest radiography and arterial blood gas analysis for the diagnosis of acute respiratory distress syndrome: a pilot study

  Number of observations (n = 33) Test characteristic 95 % CI
Study physician   Oxygenation and radiographic criteria for ARDS    
   Present Absent Sensitivity 83 % 52–98
SpO2/FiO2 ≤ 315 and UIS Present 10 8 Specificity 62 % 38–82
Absent 2 13 PPV 56 % 31–79
     NPV 87 % 60–98
   Oxygenation and radiographic criteria for moderate–severe ARDS    
   Present Absent Sensitivity 64 % 31–89
SpO2/FiO2 ≤ 235 and UIS Present 7 3 Specificity 86 % 65–97
Absent 4 19 PPV 70 % 35–93
     NPV 83 % 61–95
Independent physician   Oxygenation and radiographic criteria for ARDS    
   Present Absent Sensitivity 91 % 62–100
SpO2/FiO2 ≤ 315 and UIS Present 11 11 Specificity 48 % 26–70
Absent 1 10 PPV 50 % 28–72
     NPV 91 % 59–100
   Oxygenation and radiographic criteria for moderate–severe ARDS    
   Present Absent Sensitivity 73 % 39–94
SpO2/FiO2 ≤ 235 and UIS Present 8 5 Specificity 77 % 55–92
Absent 3 17 PPV 62 % 32–86
     NPV 85 % 62–97
  1. UIS defined as 3 or more B lines bilaterally and involving a minimum of three lung fields. CI confidence interval, FiO2 fraction of inspired oxygen, NPV negative predictive value, PaO2 partial pressure of oxygen, PPV positive predictive value, SpO2 pulse oximetric oxygen saturation