Table 1 Baseline patient characteristics
From: Persistently elevated osteopontin serum levels predict mortality in critically ill patients
Parameter | All patients | Non-sepsis | Sepsis |
|---|---|---|---|
Number | 159 | 45 | 114 |
Sex (male/female) | 99/60 | 28/17 | 71/43 |
Age median (range) (years) | 66 (20–90) | 63 (20–85) | 67 (21–90) |
APACHE II score median (range) | 18.5 (2–40) | 16.5 (2–31) | 19 (3–40) |
SAPS2 score median (range) | 44 (9–80) | 50 (30–80) | 44 (9–65) |
ICU days median (range) | 9 (1–70) | 7 (1–44) | 11 (1–70) |
Death during ICU (%) | 25.8 | 20.0 | 28.1 |
Death during ICU or follow-up (%) | 46.5 | 42.2 | 48.2 |
Ventilation yes (%) | 74.2 | 73.3 | 74.6 |
Body mass index (BMI) | 25.4 (15.9–59.5) | 25.2 (15.9–40.5) | 25.6 (16.4–59.5) |
Creatinine median (range) (mg/dl) | 1.4 (0.2–21.6) | 1 (0.2–7.9) | 1.6 (0.2–21.6) |
Albumin median (range) (g/l) | 27 (6–44) | 29.5 (18.7–44) | 25.2 (6–41) |
WBC median (range) (x103/μl) | 12.5 (0.1–208) | 12.5 (1.8–27.3) | 12.8 (0.1–208) |
CRP median (range) (mg/dl) | 140 (5–230) | 17 (5–230) | 186 (5–230) |
Procalcitonin median (range) (μg/l) | 1.2 (0.1–182.6) | 0.2 (0.1–36.5) | 3.1 (0.1–182.6) |
Interleukin 6 median (range) (pg/ml) | 97 (2–26000) | 22 (4.5–250) | 135 (2–26000) |
Tumour necrosis factor median (pg/ml) | 26 (4.1–4330) | 14 (4.1–35) | 35 (9.6–430) |
INR | 1.17 (0.94–4.64) | 1.14 (0.95–3.45) | 1.18 (0.94–4.64) |
Osteopontin at admission median (ng/ml) | 3358.5 (25.2–5884.4) | 3166.9 (36.3–5782.6) | 3504.8 (25.2–5884.4) |
Osteopontin at day 3 median (ng/ml) | 1981.8 (13.9–3613.9) | 1997.6 (361.7–3577.0) | 1948.7 (13.9–3613.9) |