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Fig. 5 | Critical Care

Fig. 5

From: Experimental acute lung injury induces multi-organ epigenetic modifications in key angiogenic genes implicated in sepsis-associated endothelial dysfunction

Fig. 5

Changes in histone H3 lysine 4 di-methylation (H3K4m2) in experimental acute lung injury-induced sepsis (ALI-sepsis). Sheared cross-linked lung, kidney, and liver chromatin from mice were assayed by using an antibody to di-methylated histone H3 lysine 4, H3K4m2. Chromatin immunoprecipitation platform (ChIP) analysis was done as in Fig. 3. Data represent mean ± standard error of the mean (n = 12 animals from each group), expressed as a fraction of input. Statistical differences are shown as in Fig. 2

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