Association between trends in clinical variables and outcome in intensive care patients with faecal peritonitis: analysis of the GenOSept cohort

Table 2 Factors independently associated with 6-month, intensive care unit, hospital and 28-day mortality, after adjustment for age and sex^a

Variable		HR	95% CI	P-value
6-month mortality
	Deterioration of thrombocytopaenia (10 × 10⁻⁹/L platelets)	1.02	1.01 to 1.03	<0.001
	Decrease in daily urinary volume (100 ml)	1.02	1.01 to 1.03	<0.001
	Decrease in highest recorded bilirubin (mmol/L)	0.99	0.99 to 0.99	0.020
	Improvement in GCS SOFA score (1 point)	0.81	0.68 to 0.98	0.028
	Improvement in renal SOFA score (1 point)	0.87	0.75 to 0.99	0.047
ICU mortality
	Decrease in daily urinary volume (100 ml)	1.02	1.01 to 1.03	0.005
	Improvement in total SOFA score (1 point)	0.91	0.85 to 0.98	0.009
Hospital mortality
	Deterioration of thrombocytopaenia (10 × 10⁻⁹/L platelets)	1.02	1.01 to 1.03	0.001
	Decrease in daily urinary volume (100 ml)	1.02	1.01 to 1.03	<0.001
	Improvement in GCS SOFA score (1 point)	0.8	0.68 to 0.95	0.011
	Improvement in renal SOFA score (1 point)	0.87	0.77 to 0.99	0.043
28-day mortality
	Decrease in daily urinary volume (100 ml)	1.02	1.01 to 1.03	0.001
	Improvement in GCS SOFA score (1 point)	0.75	0.61 to 0.93	0.010
	Improvement in renal SOFA score (1 point)	0.79	0.66 to 0.95	0.013

^aCI, Confidence interval; GCS, Glasgow Coma Scale; HR, Hazard ratio; ICU, Intensive care unit; SOFA, Sequential Organ Failure Assessment.

ISSN: 1364-8535