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Table 2 Outcome parameters for unmatched (left) and matched (right) patient population

From: Early deep sedation is associated with decreased in-hospital and two-year follow-up survival

  Unmatched Matched (APACHE II and type of admission)
  Not deeply sedated (n = 1,371) Deeply sedated (n = 513) P Not deeply sedated (n = 510) Deeply sedated (n = 510) P
Mortality (ICU) 67 (4.89%) 137 (26.7%) <0.001 37 (7.25%) 137 (26.9%) <0.001
Mortality (hospital) 131 (9.56%) 175 (34.1%) <0.001 67 (13.1%) 175 (34.3%) <0.001
Mortality (2 years) 307 (32.0%) 222 (61.8%) <0.001 126 (39.9%) 222 (62.0%) <0.001
LOS (ICU) [d] 8 [5;16] 21 [12;38] <0.001 10 [6;23] 21 [12;38] <0.001
LOS (hospital) [d] 18 [12;33] 28 [16;48] <0.001 19 [11;38] 28 [16;48] <0.001
Time to extubation [h] 17 [8;33] 75 [37;156] <0.001 21 [10;41] 76 [37;160] <0.001
Delirium 445 (32.5%) 216 (42.1%) <0.001 213 (41.8%) 216 (42.4%) 0.899
Haemodialysis during first 48 hours 153 (11.2%) 204 (39.8%) <0.001 73 (14.3%) 204 (40.0%) <0.001
NRS ≥5 or BPS ≥6 during first 48 hours 342 (24.9%) 42 (8.2%) <0.001 125 (24.5%) 42 (8.2%) <0.001
  1. ICU, intensive care unit; LOS, length of stay; NRS, numeric rating scale; BPS, behavioural pain scale.