Table 2 Outcome parameters for unmatched (left) and matched (right) patient population
From: Early deep sedation is associated with decreased in-hospital and two-year follow-up survival
Unmatched | Matched (APACHE II and type of admission) | |||||
|---|---|---|---|---|---|---|
Not deeply sedated (n = 1,371) | Deeply sedated (n = 513) | P | Not deeply sedated (n = 510) | Deeply sedated (n = 510) | P | |
Mortality (ICU) | 67 (4.89%) | 137 (26.7%) | <0.001 | 37 (7.25%) | 137 (26.9%) | <0.001 |
Mortality (hospital) | 131 (9.56%) | 175 (34.1%) | <0.001 | 67 (13.1%) | 175 (34.3%) | <0.001 |
Mortality (2 years) | 307 (32.0%) | 222 (61.8%) | <0.001 | 126 (39.9%) | 222 (62.0%) | <0.001 |
LOS (ICU) [d] | 8 [5;16] | 21 [12;38] | <0.001 | 10 [6;23] | 21 [12;38] | <0.001 |
LOS (hospital) [d] | 18 [12;33] | 28 [16;48] | <0.001 | 19 [11;38] | 28 [16;48] | <0.001 |
Time to extubation [h] | 17 [8;33] | 75 [37;156] | <0.001 | 21 [10;41] | 76 [37;160] | <0.001 |
Delirium | 445 (32.5%) | 216 (42.1%) | <0.001 | 213 (41.8%) | 216 (42.4%) | 0.899 |
Haemodialysis during first 48 hours | 153 (11.2%) | 204 (39.8%) | <0.001 | 73 (14.3%) | 204 (40.0%) | <0.001 |
NRS ≥5 or BPS ≥6 during first 48 hours | 342 (24.9%) | 42 (8.2%) | <0.001 | 125 (24.5%) | 42 (8.2%) | <0.001 |