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Table 5 Univariate and logistic regression analysis for 28-day mortality of cardiac arrest patients

From: Management and outcome of mechanically ventilated patients after cardiac arrest

Variable

Univariate analysis Odds ratio (95% CI)

P

Logistic regression Odds ratio (95% CI)

P

Age, yearsa

1.02 (1.01–1.03)

0.002

1.01 (1.00–1.03)

0.010

SAPS II score, pointsa

1.03 (1.02–1.03)

<0.001

  

Glasgow Coma Scale, pointsb

0.92 (0.88–0.95)

<0.001

  

PaO2 60–300 mmHgb

1 (reference)

 

1 (reference)

 

PaO2 <60 mmHg

2.23 (1.05–4.72)

0.036

2.71 (1.06–6.95)

0.038

PaO2 ≥300 mmHg

1.19 (0.76–1.85)

0.444

0.89 (0.54–1.46)

0.640

pHa 7.35–7.45b

1 (reference)

 

1 (reference)

 

Acidosis (pHa <7.35)

1.48 (1.07–2.04)

0.017

1.40 (0.98–2.02)

0.068

Alkalosis (pHa >7.45)

1.07 (0.67–1.71)

0.770

1.20 (0.71–2.02)

0.491

PaCO2 35–45 mmHgb

1 (reference)

   

PaCO2 <35 mmHg

1.20 (0.86–1.68)

0.277

  

PaCO2 >45 mmHg

0.94 (0.70–1.41)

0.973

  

Tidal Volume/PBWml/kgb

    

Tidal Volume/PBW 6–8 ml/kg

1 (reference)

   

Tidal Volume/PBW <6 ml/kg

1.01 (0.51–2.02)

0.975

  

Tidal Volume/PBW >8 ml/kg

0.76 ( 0.55–1.06)

0.111

  

PEEP cmH2Ob

    

PEEP 6–8 cmH2O

1 (reference)

   

PEEP <6 cmH2O

1.35 (0.94–1.95)

0.100

  

PEEP >8 cmH20

0.86 (0.52–1.42)

0.556

  

Pplat cmH2Ob

    

Pplat 28–30 cmH2O

1 (reference)

   

Pplat <28 cmH2O

0.58 (0.28–1.22)

0.149

  

Pplat >30 cmH2O

0.64 (0.22–1.89)

0.421

  

Use of sedative drugsb

0.61 (0.46–0.81)

0.001

0.51 (0.36–0.72)

0.000

Cardiovascular failure/shock (yes/no)b,c

1.53 (1.15–2.03)

<0.001

1.65 (1.17–2.32)

0.004

ARDS (yes/no)b,c

3.14 (1.41–6.97)

0.005

  

Renal failure (yes/no)b,c

1.35 (0 .95–1.91)

0.095

1.34 (0.91–1.95)

0.135

Hepatic failure (yes/no)b,c

1.20 (0.72–2.00)

0.483

  

Sepsis (yes/no)b,c

1.38 (0.88–2.18)

0.163

  

Hematologic failure (yes/no)b,c

1.05 (0.51–2.17)

0.885

  
  1. SAPS, Simplified Acute Physiology Score; PBW, predicted body weight; ml, milliliters; kg, kilograms PEEP, positive end-expiratory pressure; Pplat, plateau pressure; pHa, arterial pH; ARDS, acute respiratory distress syndrome; PaO2, partial pressure of oxygen in arterial blood; PaCO2, partial pressure of carbon dioxide in arterial blood; CI, confidence interval.
  2. aAge and SAPS score were collected as baseline characteristics, bValues within 24 hours from admission, cthe absence of organ failure as the reference value.