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Table 1 Body weight, surgery time, and hemorrhagic and resuscitation data in 19 pigs randomized to inhale nitrite, carbon monoxide, or no inhalation (control)

From: Effects of inhalation of low-dose nitrite or carbon monoxide on post-reperfusion mitochondrial function and tissue injury in hemorrhagic shock swine

 

Control (n = 7)

Nitrite (n = 7)

Carbon monoxide (n = 5)

 

Median

Range

Median

Range

P value1

Median

Range

P value1

Body weight (kg)

29.5

27.2 – 31.4

33.7

30.4 – 36.4

0.004

31.1

28.0 – 35.8

0.40

Surgery time (minutes)

70

61 – 75

75

64 – 87

0.26

78

71 – 90

0.10

Shed blood volume

        

 mL

1000

500 – 1241

1025

761 – 1452

>0.99

711

652 – 1138

0.54

 % of TBV2

51

27 – 70

46

38 – 63

>0.99

36

29 – 56

0.40

Duration (minutes)

        

 Hemorrhage 13

37

28 – 55

34

26 – 42

0.77

28

23 – 33

0.06

 Resuscitation

15

8 – 20

16

12 – 23

> 0.99

11

8 – 23

>0.99

  1. 1Nitrite and carbon monoxide groups were compared with the control group by the Mann-Whitney U test. The P values were Bonferroni-adjusted for comparison of three groups; 2TBV: total blood volume based on an assumed blood volume of 65 mL/kg; 3hemorrhage 1: time until mean arterial pressure was lower than 30 mmHg.