Effect of initial calorie intake via enteral nutrition in critical illness: a meta-analysis of randomised controlled trials

Table 1 Characteristics of the enrolled studies

Study	No. randomized		Characteristics of patients	BMI (SD)		Mean APACHE II score (SD)
Study	LE	HE	Characteristics of patients	LE	HE	LE	HE
Arabi et al. [21]	120	120	>18 years old	28.5 (7.4)	28.5 (8.4)	25.2 (7.5)	25.3 (8.2)
Arabi et al. [21]	120	120	ICU >48 hours	28.5 (7.4)	28.5 (8.4)	25.2 (7.5)	25.3 (8.2)
Braunschweig et al. [22]	38	40	>18 years old	30.1 (8.9)	29.8 (9.3)	27.7 (7.9)	23.4 (9.3)
			Medical or surgical ICU
			ALI <24 hours
Charles et al. [23]	41	42	>18 years old	32.9 (2.0)	28.1 (0.9)	16.6 (0.9)	17.3 (0.8)
			Artificial nutrition >48 hours
			ICU >48 hours
Desachy et al. [24]	50	50	>18 years old	27 (5)	25 (3)	40 (11)¹	42 (17)¹
			Medical or surgical ICU
			Mechanical ventilation >72 hours
Peake et al. [25]	55	57	≥18 years old	26.2 (6.4)	27.8 (7.9)	22 (8.9)	23 (9.1)
			Enteral nutrition ≥2 days
			Mechanical ventilation
Rice et al. [26]	98	102	ICU admission	29.2 (10.2)	28.2 (9.4)	26.9 (8.1)	26.9 (6.6)
Rice et al. [26]	98	102	Mechanical ventilation >72 hours	29.2 (10.2)	28.2 (9.4)	26.9 (8.1)	26.9 (6.6)
Rice et al. [27]	508	492	ICU admission	29.9 (7.8)	30.4 (8.2)	92 (28)²	90 (27)²
			ALI <48 hours
			Mechanical ventilation >72 hours
Taylor et al. [28]	41	41	Head injury necessitating mechanical ventilation	N/A	N/A	14³	14³
Taylor et al. [28]	41	41	Glasgow Coma Scale >3	N/A	N/A	14³	14³

¹Mean APACHE III score. ²Mean Simplified Acute Physiology Score II. ³Standard deviation was not reported. ALI, acute lung injury; APACHE, Acute Physiology And Chronic Health Evaluation; BMI, body mass index; HE, high-energy; LE, low-energy; N/A, not available; SD, standard deviation.

ISSN: 1364-8535