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Figure 1 | Critical Care

Figure 1

From: Identification of haplotype tag single nucleotide polymorphisms within the nuclear factor-κB family genes and their clinical relevance in patients with major trauma

Figure 1

Overview of selected haplotype tag single-nucleotide polymorphisms (htSNPs) within the entire NFKB2 , RELA , RELB and REL genes. Linkage disequilibrium (LD) plot of the SNPs with a minor allele frequency (MAF) ≥5% within the (A) NFKB2, (B) RELA, (C) RELB and (D) REL genes and 5-kb up- and downstream regions is displayed using an r 2 black and white color scheme. Black represents very high LD (r 2 = 1), and white indicates the absence of correlation (r 2 = 0) between SNPs. The three SNPs within the entire NFKB2 gene did not have a strong correlation between each other or with others. The htSNPs and SNPs that are indirectly measured by them are listed with corresponding r 2 values. Major and minor alleles of the selected tag SNPs are given with their frequencies, on the basis of the HapMap data for Chinese individuals from Beijing.

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Critical Care

ISSN: 1364-8535