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Table 1 Patients’ demographic data and clinical characteristics

From: Serum levels of apolipoprotein A-I and high-density lipoprotein can predict organ failure in acute pancreatitis

  Hospital survivors Hospital non-survivors P -value
(n = 53) (n = 13)
Age, years 60 (45 to 76.5) 59 (45 to 84) 0.640
Gender, M/F, number 29/24 9/4 0.532
BMI, kg/m2 25.9 ± 4.0 25.2 ± 3.7 0.597
Body weight, kg 67.6 ± 12.1 69.2 ± 11.8 0.671
Etiology, alcohol/biliary/ERCP/others 19/31/0/3 6/6/1/0 0.145
Leukocytes, ×109/l 11.8 ± 5.7 14.6 ± 0.9 0.301
Hemoglobin, g/dl 10.4 ± 2.1 10.3 ± 2.6 0.893
Platelets, ×109/l 157.5 (88.3 to 241) 62 (25 to 216) 0.043
BUN, mg/dl 17.5 (10.8 to 26.5) 44 (14.5 to 91.5) 0.009
Serum creatinine, mg/dl 0.9 (0.7 to 1.9) 3.1 (1.8 to 5.4) 0.003
Bilirubin, mg/dl 1.5 (0.9 to 3) 8 (2.7 to 22. 5) <0.001
INR 1.2 (1.1 to 1.4) 1.5 (1.2 to 1.8) 0.007
Ranson score 5 (4 to 6) 6 (6 to 8.5) 0.001
APACHE II score 15 (11 to 20.8) 28 (16.5 to 34.8) 0.002
SOFA score 5 (3 to 8) 13 (6.5 to 15.8) 0.001
Modified Marshall score 3 (2 to 5.5) 9.5 (7 to 10.8) <0.001
Organ failure 42 (79.2%) 13 (100%) 0.104
Number of organ failures 1 (1 to 2) 3 (2 to 3) <0.001
 Respiratory failure 38 (71.7%) 12 (92.3%) 0.162
 Renal failure 21 (39.6%) 11 (84.6%) 0.005
 Cardiovascular failure 13 (24.5%) 11 (84.6%) <0.001
Infected necrosis, n 10 (18.9%) 8 (61.5%) 0.002
Persistent organ failure, n 22 (41.5%) 13 (100%) <0.001
Cholesterol, mg/dl 122 (92 to 152) 98 (81 to 139) 0.256
Triglyceride, mg/dl 140 (107 to 239) 180 (102 to 362) 0.723
HDL, mg/dl 17 (11 to 31) 6 (4 to 13) <0.001
LDL, mg/dl 61 (40 to 79) 43 (30 to 91) 0.297
APO A-I, mg/dl 67 (50 to 83) 40 (23 to 46) <0.001
IL-6, pg/ml 73 (39.7 to 177.8) 388 (125 to 831.5) 0.015
TNF-α, pg/ml 6.2 (2.9 to 13.5) 25 (20 to 42) 0.011
CRP, mg/l 182.6 ± 115.6 151.6 ± 77.4 0.382
  1. Results are presented as mean ± SD, or median (IQR) unless otherwise stated. M, male; F, female; BMI, body mass index; ERCP, endoscopic retrograde cholangiopancreagraphy; BUN, blood urea nitrogen; INR, international normalized ratio; APACHE, acute physiology, age, and chronic health evaluation; SOFA, sequential organ failure assessment; HDL, high-density lipoprotein; LDL, low-density lipoprotein; APO, A-I apolipoprotein A-I; CRP, C-reactive protein.