Table 1 Patients’ demographic data and clinical characteristics
| Â | Hospital survivors | Hospital non-survivors | P -value |
|---|---|---|---|
(n = 53) | (n = 13) | ||
Age, years | 60 (45 to 76.5) | 59 (45 to 84) | 0.640 |
Gender, M/F, number | 29/24 | 9/4 | 0.532 |
BMI, kg/m2 | 25.9 ± 4.0 | 25.2 ± 3.7 | 0.597 |
Body weight, kg | 67.6 ± 12.1 | 69.2 ± 11.8 | 0.671 |
Etiology, alcohol/biliary/ERCP/others | 19/31/0/3 | 6/6/1/0 | 0.145 |
Leukocytes, ×109/l | 11.8 ± 5.7 | 14.6 ± 0.9 | 0.301 |
Hemoglobin, g/dl | 10.4 ± 2.1 | 10.3 ± 2.6 | 0.893 |
Platelets, ×109/l | 157.5 (88.3 to 241) | 62 (25 to 216) | 0.043 |
BUN, mg/dl | 17.5 (10.8 to 26.5) | 44 (14.5 to 91.5) | 0.009 |
Serum creatinine, mg/dl | 0.9 (0.7 to 1.9) | 3.1 (1.8 to 5.4) | 0.003 |
Bilirubin, mg/dl | 1.5 (0.9 to 3) | 8 (2.7 to 22. 5) | <0.001 |
INR | 1.2 (1.1 to 1.4) | 1.5 (1.2 to 1.8) | 0.007 |
Ranson score | 5 (4 to 6) | 6 (6 to 8.5) | 0.001 |
APACHE II score | 15 (11 to 20.8) | 28 (16.5 to 34.8) | 0.002 |
SOFA score | 5 (3 to 8) | 13 (6.5 to 15.8) | 0.001 |
Modified Marshall score | 3 (2 to 5.5) | 9.5 (7 to 10.8) | <0.001 |
Organ failure | 42 (79.2%) | 13 (100%) | 0.104 |
Number of organ failures | 1 (1 to 2) | 3 (2 to 3) | <0.001 |
 Respiratory failure | 38 (71.7%) | 12 (92.3%) | 0.162 |
 Renal failure | 21 (39.6%) | 11 (84.6%) | 0.005 |
 Cardiovascular failure | 13 (24.5%) | 11 (84.6%) | <0.001 |
Infected necrosis, n | 10 (18.9%) | 8 (61.5%) | 0.002 |
Persistent organ failure, n | 22 (41.5%) | 13 (100%) | <0.001 |
Cholesterol, mg/dl | 122 (92 to 152) | 98 (81 to 139) | 0.256 |
Triglyceride, mg/dl | 140 (107 to 239) | 180 (102 to 362) | 0.723 |
HDL, mg/dl | 17 (11 to 31) | 6 (4 to 13) | <0.001 |
LDL, mg/dl | 61 (40 to 79) | 43 (30 to 91) | 0.297 |
APO A-I, mg/dl | 67 (50 to 83) | 40 (23 to 46) | <0.001 |
IL-6, pg/ml | 73 (39.7 to 177.8) | 388 (125 to 831.5) | 0.015 |
TNF-α, pg/ml | 6.2 (2.9 to 13.5) | 25 (20 to 42) | 0.011 |
CRP, mg/l | 182.6 ± 115.6 | 151.6 ± 77.4 | 0.382 |