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Table 2 Hemodynamic and case dataa

From: Closed-loop assisted versus manual goal-directed fluid therapy during high-risk abdominal surgery: a case–control study with propensity matching

 

Manual

Closed-loop

P -value

Case time (min)

472 (346, 571)

433 (324, 583)

0.467

Estimated blood loss (ml)

200 (50, 400)

100 (25, 250)

0.182

Urine output (ml)

525 (345, 705)

625 (300, 900)

0.491

Total crystalloid (ml)

2500 (1,567, 3,817)

2100 (1,554, 3,653)

0.628

Crystalloid (ml/kg/hr)

4.9 (3.6, 6.4)

4.6 (3.5, 6.8)

0.977

Total colloid (ml)

750 (375, 1,050)

576 (400, 1,199)

0.938

Colloid (ml/kg/hr)

1.4 (0.7, 1.7)

1.4 (0.8, 1.6)

0.634

Blood (U/case)

0 (0, 0)

0 (0, 0)

0.760

Phenylephrine (μg)

300 (50, 700)

200 (0, 500)

0.480

Ephedrine (mg)

10 (5, 25)

10 (0, 20)

0.510

Length of SICU stay (d)

1 (0, 1)

0 (0, 2)

0.648

Length of hospital stay (d)

6 (4, 7)

6 (3, 9)

0.652

Total length of stay (d)

7 (5, 8)

6 (4, 11)

0.815

Mean HR (bpm)

78 ± 10

72 ± 10

0.035

Mean SVI (ml/m2)

43 ± 9

45 ± 10

0.615

Mean CI (L/m2/min)

3.5 ± 0.8

3.3 ± 0.8

0.373

Mean MAP (mmHg)

83 ± 9

79 ± 8

0.077

Mean SVR (dyn · s/cm5)

1070 ± 302

1121 ± 353

0.580

Mean SVV (%)

8.8 ± 2.5

7.0 ± 1.2

0.003

End HR (bpm)

88 ± 13

77 ± 10

0.003

End SVI (ml/m2)

42 ± 11

45 ± 11

0.308

End CI (L/m2/min)

3.4 ± 1.1

3.4 ± 0.9

0.811

End MAP (mmHg)

82 ± 13

78 ± 19

0.411

End SVR (dyn · s/cm5)

1042 ± 336

1033 ± 315

0.926

End SVV (%)

9.2 ± 3.1

6.9 ± 3.4

0.015*

POMS score

 

 Postoperative day 3

3 (2,4)

3 (2,4)

0.683

 Postoperative day 5

1 (1,3)

2 (1,3)

0.408

  1. abpm, Beats per minute; CI, Cardiac Index; HR, Heart rate; MAP, Mean arterial pressure; POMS, Postoperative Morbidity Survey; SICU, Surgical Intensive Care Unit; SVR, Systemic vascular resistance; SVI, Stroke Volume Index; SVV, Stroke volume variation. Data are presented as mean ± standard deviation for normally distributed scalar data, or as median (25th, 75th percentiles) for non-normally distributed scalar or ordinal data. *Primary outcome tested at P <0.05. Secondary outcome tested at P <0.025.