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Table 2 Hemodynamic and case data a

From: Closed-loop assisted versus manual goal-directed fluid therapy during high-risk abdominal surgery: a case–control study with propensity matching

  Manual Closed-loop P -value
Case time (min) 472 (346, 571) 433 (324, 583) 0.467
Estimated blood loss (ml) 200 (50, 400) 100 (25, 250) 0.182
Urine output (ml) 525 (345, 705) 625 (300, 900) 0.491
Total crystalloid (ml) 2500 (1,567, 3,817) 2100 (1,554, 3,653) 0.628
Crystalloid (ml/kg/hr) 4.9 (3.6, 6.4) 4.6 (3.5, 6.8) 0.977
Total colloid (ml) 750 (375, 1,050) 576 (400, 1,199) 0.938
Colloid (ml/kg/hr) 1.4 (0.7, 1.7) 1.4 (0.8, 1.6) 0.634
Blood (U/case) 0 (0, 0) 0 (0, 0) 0.760
Phenylephrine (μg) 300 (50, 700) 200 (0, 500) 0.480
Ephedrine (mg) 10 (5, 25) 10 (0, 20) 0.510
Length of SICU stay (d) 1 (0, 1) 0 (0, 2) 0.648
Length of hospital stay (d) 6 (4, 7) 6 (3, 9) 0.652
Total length of stay (d) 7 (5, 8) 6 (4, 11) 0.815
Mean HR (bpm) 78 ± 10 72 ± 10 0.035
Mean SVI (ml/m2) 43 ± 9 45 ± 10 0.615
Mean CI (L/m2/min) 3.5 ± 0.8 3.3 ± 0.8 0.373
Mean MAP (mmHg) 83 ± 9 79 ± 8 0.077
Mean SVR (dyn · s/cm5) 1070 ± 302 1121 ± 353 0.580
Mean SVV (%) 8.8 ± 2.5 7.0 ± 1.2 0.003
End HR (bpm) 88 ± 13 77 ± 10 0.003
End SVI (ml/m2) 42 ± 11 45 ± 11 0.308
End CI (L/m2/min) 3.4 ± 1.1 3.4 ± 0.9 0.811
End MAP (mmHg) 82 ± 13 78 ± 19 0.411
End SVR (dyn · s/cm5) 1042 ± 336 1033 ± 315 0.926
End SVV (%) 9.2 ± 3.1 6.9 ± 3.4 0.015*
POMS score  
 Postoperative day 3 3 (2,4) 3 (2,4) 0.683
 Postoperative day 5 1 (1,3) 2 (1,3) 0.408
  1. abpm, Beats per minute; CI, Cardiac Index; HR, Heart rate; MAP, Mean arterial pressure; POMS, Postoperative Morbidity Survey; SICU, Surgical Intensive Care Unit; SVR, Systemic vascular resistance; SVI, Stroke Volume Index; SVV, Stroke volume variation. Data are presented as mean ± standard deviation for normally distributed scalar data, or as median (25th, 75th percentiles) for non-normally distributed scalar or ordinal data. *Primary outcome tested at P <0.05. Secondary outcome tested at P <0.025.