Table 3 The subset of metabolites having significantly different concentrations between SS and SNS groups at either clinical time points
Sepsis survivors (number = 90) | Sepsis non-survivors (number = 31) | LPS (number = 15) | ||||
|---|---|---|---|---|---|---|
Metabolite name | Super pathway | t0 | t24 | t0 | t24 | t6 |
2-hydroxybutyrate (AHB) | Amino acid | ▲ | - | ▲ | - | ▲ |
N-acetylglycine | Amino acid | ▽ | ▽ | ▲ | ▽ | ▲ |
xylose | Carbohydrate | - | ▽ | - | ▲ | ▲ |
malate | Energy | - | ▲ | - | ▲ | ▲ |
10-nonadecenoate (19:1n9) | Lipid | - | ▲ | - | ▲ | ▲ |
2-hydroxypalmitate | Lipid | ▲ | - | ▲ | - | ▲ |
hexanoylcarnitine (C6) | Lipid | ▲ | ▲ | ▲▲ | ▲▲ | ▲ |
pregn steroid monosulfate | Lipid | ▲ | - | ▽ | - | ▲ |
3-hydroxybutyrate (BHBA) | Lipid | - | ▲ | - | ▲▲ | ▲▲ |
2-methylbutyroylcarnitine (C5) | Amino acid | ▽ | ▽ | ▲ | ▲ | ▽ |
3-indoxyl sulfate | Amino acid | - | ▽ | - | ▲ | ▽ |
5-oxoproline | Amino acid | - | ▽ | - | ▲ | ▽ |
histidine | Amino acid | - | ▽ | - | ▽ | ▽ |
isobutyrylcarnitine (C4) | Am ino acid | - | ▽ | - | ▲ | ▽ |
N-acetylornithine | Amino acid | - | ▽ | - | ▽▽ | ▽ |
tryptophan | Amino acid | - | ▽ | - | ▽ | ▽ |
threitol | Carbohydrate | - | ▽ | - | ▲ | ▽ |
phosphate | Energy | ▽ | ▽ | ▲ | ▲ | ▽ |
1-linoleoyl-GPC (18:2) | Lipid | - | ▽ | - | ▽ | ▽ |
1-oleoyl-GPC (18:1) | Lipid | - | ▽ | - | ▽ | ▽ |
2-palmitoyl-GPC (16:0) | Lipid | ▽ | ▽ | ▽▽ | ▽▽ | ▽ |
propionylcarnitine (C3) | Lipid | ▲ | ▽ | ▲ | ▲ | ▽ |
allantoin | Nucleotide | ▽ | ▽ | ▲ | ▲ | ▽ |