The diagnostic and prognostic significance of monitoring blood levels of immature neutrophils in patients with systemic inflammation

Table 3 Levels of circulating immature neutrophils are elevated in systemic inflammatory response syndrome and further increased in sepsis according to the criterion of Bone et al. , but not the criterion of Levy et al . ^a

^aN-I SIRS, Non-infectious systemic inflammatory response. Subjects were defined as having immature neutrophils when these cells were either >10% of all neutrophils (Bone et al. [2]) or >10% of all neutrophils with a normal white blood cell count (Levy et al. [3]). Results are expressed as the percentages of subjects with total immature cells, band cells only and myelocytes and metamyelocytes only. For the Bone et al. and the Levy et al. criteria comparisons were undertaken between patients with SIRS or no SIRS and normal subjects. Patients with SIRS were further subdivided into categories of definite sepsis, possible sepsis and N-I SIRS. *P <0.01; **P <0.001; ^†P <0.05; ^‡P <0.05 (χ² analysis and Fisher’s exact test).

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