From: Propofol increases morbidity and mortality in a rat model of sepsis
MPO activity [U/g] | Lung | Kidney | Spleen |
---|---|---|---|
24 hour animals (sham and CLP) | Â | Â | Â |
isoflurane-sham | 27.08(± 10.23) | 1.20(± 0.39) | 4.77(± 2.56) |
propofol-sham | 63.03(± 13.34)*** | 1.40(± 0.64) | 10.12(± 6.75)* |
isoflurane + CLP | 44.79(± 18.11)* | 2.07(± 0.67) | 4.77(± 2.56) |
sevoflurane + CLP | 41.27(± 8.68) | 1.53(± 0.57) | 7.35(± 4.25) |
desflurane + CLP | 38.00(± 9.90) | 0.87(± 0.24) | 8.61(± 3.23) |
12 hour CLP animals | Â | Â | Â |
isoflurane + CLP | 28.48(± 11.42) | 0.78(± 0.26) | 5.94(± 3.51) |
propofol + CLP | 54.20(± 9.75)### | 0.91(± 0.21) | 7.17(± 3.90) |