Skip to main content

Table 2 Demographic, clinical, and surgical characteristics of the dexamethasone and placebo groupsa

From: Effect of high-dose dexamethasone on perioperative lactate levels and glucose control: a randomized controlled trial

Characteristics

Dexamethasone (n = 247)

Placebo (n = 250)

P value

Demographics

   

 Male sex

158 (64)

159 (64)

0.83

 Age in years, mean (SD)

66.8 (11.7)

66.5 (12.0)

0.78

 Weight in kg, mean (SD)

82.1 (14.0)

82.3 (14.3)

0.91

 Height in cm, mean (SD)

173 (9.3)

173 (9.2)

0.85

Comorbidities

   

 Hypertension

146 (59)

151 (60)

0.73

 Diabetes

   

 Insulin-dependent

12 (5)

18 (7)

0.27

 Non-insulin-dependent

50 (20)

40 (16)

0.23

 Treatment for pulmonary disease

48 (19)

57 (23)

0.35

 Previous cerebrovascular event

   

 Stroke

7 (3)

12 (5)

0.55

 Transient ischemic attack

12 (5)

14 (6)

0.70

 Peripheral vascular disease

37 (15)

34 (14)

0.67

 Pre-operative serum creatinine in mg/dL, mean (SD)

1.02 (0.44)

1.02 (0.42)

0.89

Cardiac status

   

 Recent myocardial infarction (<90 days)

39 (16)

26 (10)

0.08

 Left ventricular functionb

   

  Moderate

82 (33)

93 (37)

0.33

  Poor

15 (6)

14 (6)

0.83

 EuroScore, median (IQR)c

6 (4-8)

6(4-8)

0.37

Pre-operative medication

   

 Beta-blocker

171 (69)

151 (60)

0.05

 Statin

142 (57)

125 (50)

0.13

 Corticosteroid

21 (9)

17 (7)

0.83

Type of surgery

  

0.25

 Isolated CABG

74 (30)

57 (23)

0.08

 CABG plus valve

65 (26)

66 (26)

0.96

 Single valve

95 (38)

104 (42)

0.45

 Multiple valves

8 (3)

16 (6)

0.10

 Other procedures

6 (2)

7 (3)

0.79

Repeat surgery

17 (7)

19 (8)

0.75

Duration of the procedure in minutes, mean (SD)

262 (91)

265 (86)

0.51

Duration of extracorporeal circulation in minutes, mean (SD)

147 (74)

149 (69)

0.70

Duration of aortic cross-clamping in minutes, mean (SD)

95 (49)

99 (46)

0.43

Type of anesthesia maintenance

  

0.92

 Propofol

133 (53.6)

132 (52.8)

 

 Volatile

115 (46.4)

118 (47.2)

 

Use of cell-saving device

17 (7)

23 (9)

0.34

Use of antifibrinolytic agent

179 (72)

179 (72)

0.72

  1. International System conversion: To convert creatinine to μmol/L, multiply by 88.4. aData presented as number (percentage) unless otherwise indicated. bDefinition of left ventricular function classes: moderate, ejection fraction of 30% to 50%; and poor, ejection fraction of less than 30% [24]. cHigher EuroScores indicate increased risk of perioperative mortality [24]. CABG, coronary artery bypass grafting; IQR, interquartile range; SD, standard deviation.
Back to article page

Critical Care

ISSN: 1364-8535