Outcome measurea | Dexamethasone (n = 62) | Placebo (n = 58) | P value |
---|---|---|---|
Glucose AUC15 in mmol/L × hour | 132.8 (16.2) | 124.8 (16.5) | 0.009 |
Glucose level in mmol/L at postoperative ICU admission | 10.0 (2.5) | 8.0 (2.3) | <0.001 |
Hyperglycemic index in mmol/Lb (cutoff >6.0 mmol/L) | 2.70 (1.00) | 2.21 (1.00) | 0.009 |
Hyperglycemic index in mmol/Lc (cutoff >8.0 mmol/L) | 1.14 (0.91) | 0.77 (0.76) | 0.017 |
Hypoglycemia incidence, N (%)d | 0 (0) | 3 (5.2) | 0.110 |
Lactate AUC15 in mmol/L × hour | 25.9 (9.7) | 22.1 (16.2) | 0.119 |
Lactate level in mmol/L at postoperative ICU admission | 2.1 (1.0) | 1.7 (0.7) | 0.007 |
Insulin consumption in IU at first 15 hours of ICU admission | 46.6 (22.9) | 28.3 (19.7) | <0.001 |