Table 2 Overall clinical characteristics of patients with major trauma
| Ā | Screening cohort | Validation cohorts | |
|---|---|---|---|
Chongqing (Nā=ā837) | Zhejiang (Nā=ā340) | Yunnan (Nā=ā367) | |
Age (yrs) | 41.1āĀ±ā13.4 (18-65) | 42.5āĀ±ā12.0 (19-65) | 37.6āĀ±ā12.5 (18-65) |
Male/female, n | 672/165 | 266/74 | 282/85 |
Injured body regions, n (%) | Ā | Ā | Ā |
āHead, n | 458 (54.7) | 248 (72.9) | 225 (61.3) |
āThorax, n | 513 (61.2) | 209 (61.5) | 186 (50.7) |
āAbdomen, n | 389 (46.4) | 118 (34.7) | 105 (28.6) |
āExtremities, n | 425 (50.8) | 179 (52.6) | 196 (53.4) |
Number of regions injured, n (%) | Ā | Ā | Ā |
āOne, n | 435 (52.0) | 146 (42.9) | 157 (42.8) |
āTwo, n | 267 (31.9) | 129 (37.9) | 131 (35.7) |
āThree or above, n | 135 (16.1) | 65 (19.1) | 79 (21.5) |
ISS | 22.3āĀ±ā9.4 | 21.7āĀ±ā7.7 | 21.3āĀ±ā9.2 |
āā„16, <25, n (%) | 510 (60.9) | 197 (57.9) | 228 (62.1) |
āā„25, n (%) | 327 (39.1) | 143 (42.1) | 139 (37.9) |
Organ dysfunction, n (%) | Ā | Ā | Ā |
āOne, n | 268 (32.2) | 112 (32.9) | 125 (34.1) |
āTwo, n | 121 (14.5) | 56 (16.5) | 51 (13.9) |
āThree or above, n | 41 (4.9) | 23 (6.8) | 35 (9.5) |
Sepsis, n (%) | 346 (41.3) | 129 (37.9) | 130 (35.4) |
Source of infection, % | Ā | Ā | Ā |
āRespiratory tract infection | 41.6 | 39.7 | 43.2 |
āPrimary bloodstream infection | 21.5 | 24.1 | 19.9 |
āUrinary tract infection | 16.2 | 11.2 | 12.1 |
āCatheter-associated infection | 10.9 | 9.1 | 9.3 |
āWound infection | 7.4 | 9.1 | 10.1 |
āOthers* | 2.4 | 6.8 | 5.4 |
Pathogens, % (positive blood cultures) | Ā | Ā | Ā |
Gram-negative | 22.3 | 25.7 | 29.5 |
Gram-positive | 17.6 | 13.2 | 12.8 |
Fungi | 2.8 | 3.5 | 3.6 |
Mixed Gram-negative and -positive | 5.9 | 7.5 | 8.5 |
Negative blood cultures | 54.0 | 55.0 | 57.0 |