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Table 2 Haemodynamic parameters

From: Adjusting tidal volume to stress index in an open lung condition optimizes ventilation and prevents overdistension in an experimental model of lung injury and reduced chest wall compliance

Parameters

T0

T1

T2

T3

T4

IC

     

Pplat-group

3.0 (0.9)

2.6 (0.3)

3.0 (0.3)

2.5 (0.8)

2.9 (0.5)

SI-group

3.2 (0.8)

2.7 (0.4)

2.6 (0.4)

2.4 (0.2)

2.5 (0.4)

P-value

0.69

0.76

0.08

0.86

0.16

AM

     

Pplat-group

103 (11)

99 (12)

105 (8)

93 (15)

91 (28)

SI-group

101 (7)

97 (9)

97 (17)

103 (19)

101 (18)

P-value

0.72

0.81

0.41

0.40

0.56

FC

     

Pplat-group

74 (8)

72 (13)

78 (25)

83 (38)

88 (25)

SI-group

85 (15)

64 (7)

70 (28)

74 (28)

82 (35)

P-value

0.19

0.24

0.64

0.38

0.77

ITBVI

     

Pplat-group

521 (123)

492 (41)

551 (63)

542 (195)

568 (72)

SI-group

528 (105)

580 (100)

676 (107)

660 (153)

644 (107)

P-value

0.93

0.10

0.05

0.32

0.07

EVLWI

     

Pplat-group

8 (2)

18 (5)

15 (3)

14 (3)

15 (4)

SI-group

8 (1)

17 (2)

18 (4)

18 (4)

18 (4)

P-value

0.86

0.78

0.34

0.18

0.27

PVPI

     

Pplat-group

1.9 (0.8)

3.8 (1.4)

3.5 (0.8)

2.7 (0.7)

2.9 (0.8)

SI-group

2.2 (0.6)

3.2 (0.6)

3.0 (0.9)

2.8 (0.5)

2.8 (0.5)

P-value

0.61

0.44

0.40

0.68

0.93

  1. Time-points T0: Baseline measurement, 10 minutes after protocolized baseline ventilatory parameters, before lung injury. T1: 60, T2: 120, T3: 180 and T4: 240 minutes after protocolized ventilatory parameters (open lung PEEP and protocolized VT corresponding to the study group) were adjusted. Data are presented as mean (SD). IC: cardiac index (ml/min/m2), MAP: mean arterial pressure (mmHg), FC: cardiac frequency (bpm), ITBVI: intra-thoracic blood volume indexed to predicted body weight (ml/m2), EVLWI: extravascular lung water indexed to predicted body weight (ml/m2), PVPI: pulmonary vascular permeability index.
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Critical Care

ISSN: 1364-8535