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Table 3 Moderator analyses for studies on patients resuscitated from cardiac arrest (k = 5)

From: Arterial hyperoxia and mortality in critically ill patients: a systematic review and meta-analysis

 

k

Effect size (OR)

95% CI

P

Q

I 2

P a

Study design

      

0.836

Multicenter

3

1.46

1.03-2.07

0.031

8.15*

75.45

 

Single-center

2

1.30

0.46-3.70

0.622

4.10*

75.60

 

Hyperoxia, definition

      

0.017

First PaO2

1

1.80

1.50-2.20

0.000

-

-

 

Highest PaO2

2

1.30

0.46-3.70

0.622

4.10*

75.60

 

Worst PaO2

2

1.21

0.99-1.47

0.064

0.06

0.00

 

Comparator group

      

0.381

Not exposed to hyperoxia

3

1.54

0.93-2.54

0.095

5.23

61.78

 

Normoxia

2

1.21

0.99-1.47

0.064

0.06

0.00

 

Outcome data

      

0.791

Adjusted

2

1.47

0.99-2.19

0.057

8.12**

87.69

 

Unadjusted

3

1.32

0.68-2.58

0.409

4.10

51.21

 
 

k

Beta

P

    

Study quality

       

NOS score

5

−0.24

0.184

    

Chronic cardiovascular disease

       

Percentage

4

−0.04

0.024

    
  1. aAnalysis of variance Q-test between study subgroups. *P <0.05; **P <0.01. k, number of studies; OR, odds ratio; CI, confidence interval; Q, test for heterogeneity; I2, inconsistency between studies; PaO2, arterial partial oxygen pressure; Beta, coefficient of the random effects meta-regression analysis: positive and negative values indicate direct and inverse relationships, respectively; NOS Newcastle-Ottawa Scale.
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