Early high protein intake is associated with low mortality and energy overfeeding with high mortality in non-septic mechanically ventilated critically ill patients

Table 2 Logistic regression analysis

	Odds ratio	95% CI	P -value
All patients (n = 843)
Protein intake group^a	0.85	0.73, 0.99	0.047
Energy overfeeding (yes/no)	1.62	1.07, 2.44	0.022
Sepsis (yes/no)	1.77	1.18, 2.65	0.005
APACHE II score	1.04	1.02, 1.05	<0.001
Septic patients (n = 117)
Protein intake group^a	1.15	0.80, 1.66	0.460
Energy overfeeding (yes/no)	0.82	0.35, 2.29	0.821
APACHE II score	1.03	0.98, 1.08	0.208
Non-septic patients (n = 726)
Protein intake group^a	0.80	0.67, 0.95	0.011
Energy overfeeding (yes/no)	1.89	1.19, 3.02	0.007
APACHE II score	1.04	1.01, 1.06	0.001
Non-septic overfed patients (n = 307)
Protein intake group^a	0.91	0.59, 1.40	0.666
APACHE II score	1.04	1.00, 1.07	0.029
Non-septic non-overfed patients (n = 419)
Protein intake group^a	0.77	0.63, 0.93	0.008
APACHE II score	1.03	1.01, 1.06	0.013

^aProtein intake groups were <0.8, 0.8 to <1.0, 1.0 to <1.2, and ≥1.2 g/kg. P-values in bold indicate a significant test result. APACHE, acute physiology and chronic health evaluation.

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