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Table 5 Clinically orientated secondary outcomes

From: Physiological changes after fluid bolus therapy in sepsis: a systematic review of contemporary data

First author Journal Year Control group LOS in ICU (days) LOS in hospital (days) MV (days) CRRT Intervention group LOS in ICU (days) LOS in hospital (days) MV (days) CRRT
MacRedmond [ [49]] Quality and Safety in Health Care 2010 Before protocolised resuscitation 8     After protocolised resuscitation 7    
Castellanos-Ortega [ [37]] Critical Care Medicine 2010 Pre-intervention 9.9 26.5    Intervention group, significantly more receive fluid 9.1 30.6   
Hanzelka [ [43]] Supportive Care in Cancer 2013 Pre-intervention 5.1 10.3    Post-intervention, significantly quicker resuscitation 2.5 8.1   
Trof [ [64]] Critical Care Medicine 2012 Pulmonary artery catheter-guided resuscitation 15 25 13   Transpulmonary thermodilution-guided resuscitation 11 27 10  
Patel [ [58]] Annals of Pharmacotherapy 2010 Pre-intervention 6 9.5 7.5 8/53 Post-intervention, significantly more fluid and less vasoactives 5 9 7 0/59
  1. CRRT, continuous renal replacement therapy; LOS, length of stay; MV, mechanical ventilation.