Table 5 Clinically orientated secondary outcomes
From: Physiological changes after fluid bolus therapy in sepsis: a systematic review of contemporary data
First author | Journal | Year | Control group | LOS in ICU (days) | LOS in hospital (days) | MV (days) | CRRT | Intervention group | LOS in ICU (days) | LOS in hospital (days) | MV (days) | CRRT |
|---|---|---|---|---|---|---|---|---|---|---|---|---|
MacRedmond [ [49]] | Quality and Safety in Health Care | 2010 | Before protocolised resuscitation | 8 | Â | Â | Â | After protocolised resuscitation | 7 | Â | Â | Â |
Castellanos-Ortega [ [37]] | Critical Care Medicine | 2010 | Pre-intervention | 9.9 | 26.5 | Â | Â | Intervention group, significantly more receive fluid | 9.1 | 30.6 | Â | Â |
Hanzelka [ [43]] | Supportive Care in Cancer | 2013 | Pre-intervention | 5.1 | 10.3 | Â | Â | Post-intervention, significantly quicker resuscitation | 2.5 | 8.1 | Â | Â |
Trof [ [64]] | Critical Care Medicine | 2012 | Pulmonary artery catheter-guided resuscitation | 15 | 25 | 13 | Â | Transpulmonary thermodilution-guided resuscitation | 11 | 27 | 10 | Â |
Patel [ [58]] | Annals of Pharmacotherapy | 2010 | Pre-intervention | 6 | 9.5 | 7.5 | 8/53 | Post-intervention, significantly more fluid and less vasoactives | 5 | 9 | 7 | 0/59 |