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Table 1 Hazard ratios (95% CI) of the effect of tranexamic acid on all-cause mortality, bleeding and non-bleeding deaths by day since injury

From: Mechanism of action of tranexamic acid in bleeding trauma patients: an exploratory analysis of data from the CRASH-2 trial

Days since injury

All-cause

Bleeding

Non-bleeding

0

0.83 (0.73, 0.93)

0.80 (0.68, 0.94)

0.87 (0.71, 1.06)

1

0.91 (0.79, 1.04)

0.89 (0.72, 1.11)

0.92 (0.76, 1.11)

2

0.96 (0.77, 1.19)

1.17 (0.74, 1.86)

0.91 (0.71, 1.16)

3

1.01 (0.76, 1.34)

0.66 (0.32, 1.37)

1.09 (0.80, 1.48)

4

0.96 (0.70, 1.36)

0.77 (0.29, 2.06)

1.01 (0.71, 1.43)