Methylglyoxal as a new biomarker in patients with septic shock: an observational clinical study

Table 3 Plasma levels of C-reactive protein, procalcitonin, interleukin-6, soluble CD14 subtype, blood glucose, and total antioxidant capacity in the volunteer (V/T0), postoperative (P/T0, P/T1, P/T2), and septic (S/T0, S/T1) groups

Parameters	Volunteer group (n = 30)	Postoperative group (n = 30)						Septic group (n = 60)
Parameters	V/T0	P/T0		P/T1		P/T2		S/T0		S/T1
CRP, mg/L	2.0	4.3	*******	4.3	*******	110.2	*******	169.2	*******	190.4	*******
PCT, μg/L	0.06	0.07	ns	0.10	**	0.82	*******	4.63	*******	7.17	*******
IL-6, pg/mL	0.0	0.0	**	215.3	*******	132.5	*******	500.5	*******	337.6	*******
sCD14-ST, pg/mL	123.0	208.5	*******	711.0	*******	680.0	*******	1817.5	*******	2309.0	*******
Blood glucose, mg/dL	85.0	102.5	**	140.0	*******	116.0	*******	128.5	*******	139.0	*******
TAC, mM	0.02	0.06	*******	0.10	*******	0.12	*******	0.15	*******	0.13	*******

Data are presented as medians. Results of pairwise comparisons refer to intergroup comparisons of each presented time point in the postoperative (P/T0, P/T1, P/T2) and septic (S/T0, S/T1) groups with the volunteer group (V/T0). With regard to symbolism and higher orders of significance: *P <0.05; **P <0.01; ***P <0.001; ns, not statistically significant. The central lab of the University Hospital of Heidelberg provides precise values for C-reactive protein (CRP) beginning from 2 mg/L. Lower CRP values are simply denoted less than 2.0 mg/L. For statistical analyses, all values less than 2.0 mg/L were put on a level of 2.0 mg/L. Precise values for PCT are available beginning from 0.05 μg/L. Lower PCT values are simply denoted less than 0.05 μg/L. For statistical analyses, all values less than 0.05 μg/L were put on a level of 0.05 μg/L. IL-6, interleukin-6; PCT, procalcitonin; sCD14-ST, soluble CD14 subtype; TAC, total antioxidant capacity.

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