Plasma glutamine concentrations in ICU patients given exogenous intravenous glutamine supplementation together with full nutrition for >3 days and who were discharged alive from ICU, in relation to 12-month, post-ICU mortality. (A) illustrates discharge glutamine level (n = 63), and (B) illustrates glutamine levels 24 to 72 hours post discharge (n = 92). Discharge glutamine level during ongoing intravenous supplementation but not post-ICU glutamine level was associated with mortality outcome. Gray shading indicates the reference interval used, 400 to 930 μmol/L. Horizontal lines indicate median values. ICU, intensive care unit.