CONSORT diagrams on patients screened and included in the studies. Patients admitted to the ICU) and given exogenous intravenous glutamine supplementation together with full nutrition for >3 days were eligible. (A) describes patients sampled on their last day of ICU stay and thereafter every 5 to 7 days during the remaining hospital stay. Mortality, dropouts and ICU readmissions are indicated. (B) describes patients discharged from the ICU and sampled 24 to 72 hours after discharge. Mortality and dropouts are indicated. ICU, intensive care unit.