Table 3 Renal effects of atenolol in ovine sepsis

Urine (mL/h)

A

24.2 (17.3;33.7)

19.7 (12.2;31.9)

15.8 (9.8;25.6)

10.6 (6.5;17.3)

17.9 (11.0;29.0)

C

22.2 (15.9;31.0)

30.3 (18.5;49.5)

21.2 (13.1;34.4)

14.2 (8.8;23.0)

14.7 (9.1;23.9)

P-creat (μmol/L)

A

73 (60;88)

108 (90; 130)^†

123 (100;150)^†

138 (113;168)^†

158 (131;191)^†

C

62 (51;75)

84 (70;101)

90 (73;109)

97 (79;118)^†

132 (110;160)^†

CreatCl (mL/min)

A

58.5 ± 7.1

30.9 ± 7.0^†

26.5 ± 7.7^†

16.4 ± 7.7^†

36 ± 7.1

C

66.1 ± 7.1

43.4 ± 7.0^†

45.3 ± 7.7

37.5 ± 7.7^†

39.7 ± 7.1^†

FENa (%)

A

0.21 (0.11;0.43)

0.42 (0.21;0.85)

0.32 (0.16;061)

0.51 (0.26;0.98)

0.13 (0.07:0.26)

C

0.18 (0.09;0.39)

0.48 (0.24;0.96)

0.26 (0.14;0.50)

0.20 (0.10;0.38)

0.08 (0.04;0.15)

FEK (%)

A

29.7 ± 3.9

25.7 ± 3.9

26.3 ± 4.9

27.9 ± 4.9

27.2 ± 3.9

C

23.7 ± 3.9

25 ± 3.9

20.2 ± 4.9

18.0 ± 4.9

25.9 ± 3.9

FEUN (%)

A

48.2 ± 7.6

35.9 ± 7.1

32.3 ± 7.2

31.2 ± 7.2

17.5 ± 7.1^†

C

47.9 ± 7.1

42.7 ± 7.1

31.5 ± 7.2

29.4 ± 7.2

22.0 ± 7.1^†