Table 5 Univariate analysis of bad neurologic evolution (pediatric cerebral performance category (PCPC) >2) according to post-return of spontaneous circulation (ROSC) factors
Patients, % | PCPC >2, % | Odds ratio | 95% CI | P -value | |
|---|---|---|---|---|---|
Patients | |||||
Mechanical ventilation | |||||
No | 4.7 | 16.7 | 1.000 | ||
Yes | 95.3 | 30.9 | 2.235 | 0.252 to 19.791 | 0.470 |
Vasoactive drugs | |||||
No | 42.1 | 18.4 | 1.000 | ||
Yes | 57.9 | 36 | 1.739 | 0.793 to 3.186 | 0.167 |
Adrenaline | |||||
No | 80.6 | 31 | 1.000 | ||
Yes | 19.4 | 28.6 | 0.889 | 0.358 to 2.207 | 0.800 |
Noradrenaline | |||||
No | 87.5 | 30.2 | 1.000 | ||
Yes | 12.5 | 33.3 | 1.158 | 0.405 to 3.313 | 0.785 |
Dopamine | |||||
No | 63.2 | 27.5 | 1.000 | ||
Yes | 36.8 | 35.8 | 1.475 | 0.714 to 3.049 | 0.294 |
Dobutamine | |||||
No | 74.3 | 24.3 | 1.000 | ||
Yes | 25.7 | 48.6 | 2.951 | 1.351 to 6.448 | 0.007 |
Milrinone | |||||
No | 82.6 | 32.8 | 1.000 | ||
Yes | 17.4 | 20 | 0.513 | 0.179 to 1.469 | 0.213 |
Vasoactive-inotropic score | |||||
<14 | 48.1 | 43.2 | 1.000 | ||
>14 | 51.9 | 35 | 0.707 | 0.282 to 1.772 | 0.459 |
Echocardiographic rhythm after ROSC | |||||
Sinus rhythm | 74 | 27.8 | 1.000 | ||
Other rhythms | 26 | 36.8 | 1.497 | 0.685 to 3.274 | 0.312 |
Recovery of spontaneous breathing | |||||
Yes | 65.3 | 25.5 | 1.000 | ||
No | 34.7 | 33.3 | 1.340 | 0.648 to 2.767 | 0.430 |
pH 1 h | |||||
7.30 to 7.50 | 40.8 | 21.6 | 1.000 | ||
<7.30 | 54.4 | 32.4 | 1.739 | 0.752 to 4.023 | 0.196 |
>7.50 | 4.8 | 33.3 | 1.818 | 0.293 to 11.265 | 0.521 |
PaO 2 1 h | |||||
60 to 200 mmHg | 45.2 | 33.3 | 1.000 | ||
<60 mmHg | 40.5 | 29.4 | 0.833 | 0.368 to 1.885 | 0.661 |
>200 mmHg | 14.3 | 16.7 | 0.400 | 0.103 to 1.553 | 0.186 |
PaCO 2 1 h | |||||
30 to 50 mmHg | 62.1 | 23.4 | 1.000 | ||
<30 mmHg | 9.7 | 50 | 3.278 | 0.940 to 11.425 | 0.062 |
>50 mmHg | 28.2 | 37.1 | 1.937 | 0.815 to 4.601 | 0.134 |
CO 3 H 1 h | |||||
20 to 26 mEq/L | 34.7 | 23.8 | 1.000 | ||
<20 mEq/L | 44.6 | 38.9 | 2.036 | 0.831 to 4.991 | 0.120 |
>26 mEq/L | 20.7 | 20 | 0.800 | 0.239 to 2.683 | 0.718 |
BE | |||||
+4 to -4 | 24.8 | 25 | 1.000 | ||
<-4 | 61.1 | 33.3 | 1.500 | 0.557 to 4.041 | 0.423 |
> + 4 | 14.2 | 18.8 | 0.692 | 0.152 to 3.163 | 0.635 |
FiO 2 1 h | |||||
<0.50 | 50.9 | 25.5 | 1.000 | ||
0.50 to 0.79 | 25.9 | 32.1 | 1.125 | 0.324 to 3.909 | 0.853 |
≥0.80 | 23.1 | 44 | 1.125 | 0.409 to 3.097 | 0.820 |
PaO 2 /FiO 2 1 h | |||||
>300 | 15.9 | 16.7 | 1.000 | ||
200 to 300 | 12.4 | 14.3 | 3.049 | 0.083 to 11.149 | 0.092 |
<200 | 71.7 | 34.6 | 1.286 | 0.224 to 7.370 | 0.778 |
Lactic acid 1 h | |||||
<2 mmol/L | 21.3 | 6.2 | 1.000 | ||
2 to 5 mmol/L | 37.3 | 25 | 3.520 | 0.675 to 18.366 | 0.135 |
>5 mmol/L | 41.3 | 41.9 | 9.263 | 1.883 to 45.560 | 0.006 |
pH 24 h | |||||
7.30 to 7.50 | 80.6 | 26 | 1.000 | ||
<7.30 | 12.9 | 43.8 | 2.214 | 0.749 to 6.545 | 0.151 |
>7.50 | 6.5 | 62.5 | 4.744 | 1.059 to 21.248 | 0.042 |
PaO 2 24 h | |||||
60 to 200 mmHg | 58.5 | 29.2 | 1.000 | ||
< 60 mmHg | 36.6 | 37.8 | 1.474 | 0.670 to 3.243 | 0.334 |
>200 mmHg | 4.9 | 0 | 0 | ||
PaCO 2 24 h | |||||
30 to 50 mmHg | 76.9 | 24.1 | 1.000 | ||
<30 mmHg | 5.6 | 50 | 3.150 | 0.589 to 16.859 | 0.180 |
>50 mmHg | 17.6 | 52.6 | 3.500 | 1.248 to 9.819 | 0.017 |
CO 3 H 24 h | |||||
20 to 26 mEq/L | 43 | 26.9 | 1.000 | ||
<20 mEq/L | 15.7 | 26.3 | 0.969 | 0..295 to 3.189 | 0.959 |
>26 mEq/L | 41.3 | 36 | 1.527 | 0.658 to 3.544 | 0.325 |
BE 24 h | |||||
+4 to -4 | 50 | 19.6 | 1.000 | ||
<-4 | 23.2 | 38.5 | 2.557 | 0.914 to 7.155 | 0.774 |
> + 4 | 26.8 | 46.7 | 3.580 | 1.351 to 9.482 | 0.010 |
FiO 2 24 h | |||||
<0.50 | 21.4 | 28 | 1.000 | ||
0.50 to 0.79 | 19.7 | 30.4 | 1.387 | 0.511 to 3.765 | 0.521 |
≥0.80 | 59 | 30.4 | 2.301 | 0.850 to 6.229 | 0.100 |
PaO 2 /FiO 2 24 h | |||||
>300 | 21 | 13.6 | 1.000 | ||
200 to 300 | 17.1 | 22.2 | 3.128 | 0.974 to 10.049 | 0.056 |
<200 | 61.9 | 40 | 1.312 | 0.284 to 6.067 | 0.728 |
Lactic acid 24 h | |||||
<2 mmol/L | 66.7 | 26.9 | 1.000 | ||
2 to 5 mmol/L | 20.5 | 31.2 | 1.234 | 0.364 to 4.187 | 0.736 |
>5 mmol/L | 12.8 | 40 | 1.810 | 0.444 to 7.380 | 0.408 |