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Table 3 Risk of acute kidney injury with albumin administration in propensity-matched patients a

From: Albumin administration is associated with acute kidney injury in cardiac surgery: a propensity score analysis

 

No albumin ( n = 141)

Any albumin ( n = 141)

P -value

Age (yr)

70 ± 9

69 ± 9

0.81

GFR (ml/min/1.73 m2)

62 ± 18

62 ± 20

0.78

LVEF ≤35%, 36% to 49%, ≥50% (%)

14, 11, 75

13, 19, 68

0.13

Preoperative hemoglobin (g/L)

127 ± 18

127 ± 19

0.99

Diuretics (%)

50

50

1.00

Heart valve surgery (%)

35

31

0.45

Duration of ECC (hr)

1.5 ± 0.7

1.6 ± 0.8

0.94

Cardiovascular SOFA score (immediately postoperatively) ≤2, >2 (%)

34, 66

38, 62

0.52

Crystalloids perioperatively until 36 hr postoperativelyb (ml/kg)

82 ± 35

78 ± 30

0.28

Any HES 6% perioperatively until 36 hr postoperatively (%)

85

91

0.10

Dose of HES 6% receivedb (ml/kg)

16 (9 to 23)

14 (8 to 20)

0.30

Any pentastarch 10% perioperatively until 36 hr after surgery (%)

38

36

0.71

Dose of pentastarch 10% receivedb (ml/kg)

13 (8 to 18)

8 (5 to 16)

0.03

Red blood cell transfusions, 0, 1, 2, 3+ U (%)

30, 9, 15, 45

19, 16, 20, 45

0.07

Fresh frozen plasma transfusions, 0, ≤5, >5 U (%)

67, 28, 5

67, 23, 10

0.70

Platelet transfusions, 0, ≤10, >10 U (%)

73, 23, 4

71, 22, 7

0.59

AKI

   

  AKIN stage 1 (%)

13

28

0.002

  RIFLE risk (%)

5

12

0.03

  RIFLE injury (%)

1

5

0.09

  1. aAKI, Acute kidney injury; AKIN, Acute Kidney Injury Network; ECC, Extracorporeal circulation; GFR, Glomerular filtration rate; HES, Hydroxyethyl starch; LVEF, Left ventricular ejection fraction; RIFLE, Risk, injury, failure, loss and end-stage kidney disease; SOFA, Sequential Organ Failure Assessment. bThe median (interquartile range (IQR)) value given applies to the subgroup that received the colloid.