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Table 2 Variables associated with acute kidney injury as defined by RIFLE risk a

From: Albumin administration is associated with acute kidney injury in cardiac surgery: a propensity score analysis

 

No AKI ( n = 932)

AKI ( n = 52)

P -value

Preoperative LVEF, ≤35%, 36% to 49%, ≥50% (%)

9, 13, 78

15, 21, 64

0.02

Preoperative use of diuretics (%)

33

56

0.001

Preoperative hemoglobin (g/L)

130 ± 17

123 ± 22

0.002

Heart valve surgery (%)

22

37

0.01

Duration of ECC (hr)

1.21 ± 0.62

1.59 ± 0.79

<0.001

Use of intra-aortic balloon pump (%)

6

14

0.03

Postoperative cardiovascular SOFA score 0 or 1, 2, 3 or 4 (%)

51, 0, 49

27, 2, 71

<0.001

Any perioperative transfusions (%)

   

  Red blood cells

50

79

<0.001

  Fresh frozen plasma

20

35

0.005

  Platelets

19

37

<0.001

Any pentastarch 10% receivedb (%)

43

56

0.06

Any albumin received (%)

14

38

<0.001

  1. aResults are expressed as mean ± standard deviation, median (interquartile range) or percent, as appropriate. bThe dose of pentastarch was associated with acute kidney injury (AKI) (see Figure 3). Sex, age, ethnicity, smoking status, prior history, initial estimated glomerular filtration rate, other medication, urgent surgery, need for reintervention and amount of crystalloids and hydroxyethyl starch 6% were not statistically associated with AKI. ECC, extracorporeal circulation; LVEF, left ventricular ejection fraction; SOFA, Sequential Organ Failure Assessment score.
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