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Table 2 Variables associated with acute kidney injury as defined by RIFLE risk a

From: Albumin administration is associated with acute kidney injury in cardiac surgery: a propensity score analysis

  No AKI ( n = 932) AKI ( n = 52) P -value
Preoperative LVEF, ≤35%, 36% to 49%, ≥50% (%) 9, 13, 78 15, 21, 64 0.02
Preoperative use of diuretics (%) 33 56 0.001
Preoperative hemoglobin (g/L) 130 ± 17 123 ± 22 0.002
Heart valve surgery (%) 22 37 0.01
Duration of ECC (hr) 1.21 ± 0.62 1.59 ± 0.79 <0.001
Use of intra-aortic balloon pump (%) 6 14 0.03
Postoperative cardiovascular SOFA score 0 or 1, 2, 3 or 4 (%) 51, 0, 49 27, 2, 71 <0.001
Any perioperative transfusions (%)    
  Red blood cells 50 79 <0.001
  Fresh frozen plasma 20 35 0.005
  Platelets 19 37 <0.001
Any pentastarch 10% receivedb (%) 43 56 0.06
Any albumin received (%) 14 38 <0.001
  1. aResults are expressed as mean ± standard deviation, median (interquartile range) or percent, as appropriate. bThe dose of pentastarch was associated with acute kidney injury (AKI) (see Figure 3). Sex, age, ethnicity, smoking status, prior history, initial estimated glomerular filtration rate, other medication, urgent surgery, need for reintervention and amount of crystalloids and hydroxyethyl starch 6% were not statistically associated with AKI. ECC, extracorporeal circulation; LVEF, left ventricular ejection fraction; SOFA, Sequential Organ Failure Assessment score.