Early n = 101 | Late n = 104 | P-value | |
---|---|---|---|
28-day mortality | 20 (20%; 13 to 29) | 30 (29%; 20 to 38) | 0.1317 |
90-day mortality | 30 (30%; 21 to 40) | 44 (42%; 33 to 52) | 0.0603 |
Hospital mortality | 31 (31%; 22 to 41) | 45 (43%; 34 to 53) | 0.0623 |
Days free of mechanical ventilation, 28-day | 8 (0, 22) | 4 (0, 22) | 0.0003 |
Days free of mechanical ventilation, 90-day | 70 (24 to 84) | 66 (0 to 84) | 0.0002 |
Duration of sedation | 11 (2 to 66) | 16.5 (5 to 63) | 0.0006 |
ICU length of stay | 24 (6 to 84) | 29 (6 to 174) | 0.0276 |
Other characteristics related to mechanical ventilation and tracheotomy | |||
Weaning protocol applied in intubated patients | 16 (16%; 9 to 24) | 27 (26%; 18 to 36) | 0.0752 |
Failed extubation (reintubated) | 13 (13%; 6 to 20) | 11 (11%; 5 to 18) | 0.6095 |
Days of intubation in tracheotomized patients | 7 (5 to 7) | 14 (14 to 22) | 0.0000 |
Days of intubation in successfully extubated patients | 0 | 14 (11 to 17) | |
Patients sedated, n, % | 95 (94%; 87 to 98) | 102 (98%; 93 to 99) | 0.1375 |
Deep sedation with neuroblocker drugs | 19 (19%; 12 to 28) | 27 (26%; 18 to 36) | 0.2199 |
Maximum positive end-expiratory pressure | 7 (2 to 16) | 7 (3 to 15) | 0.8966 |
Ventilator-associated pneumonia | 11 (11%; 6 to 19) | 12 (12%; 6 to 19) | 0.8833 |
Early complications of tracheotomy | 2 (2%;0.3-7) | 5 (6.6%; 1.5-11) | 0.2417 |