Table 2 Subgroup analyses of overall mortality ^a

All trials [6],[7],[16]-[26]

13

2,525

0.83 (0.71 to 0.96)

0.01

56

  Early [6],[7],[16],[22],[24]-[26]

7

2,062

0.77 (0.67 to 0.89)

0.0004

40

  Late or unclear [17]-[21],[23]

6

463

0.92 (0.69 to 1.24)

0.59

56

  Low [6],[7],[19],[21],[22]

5

1,626

0.92 (0.75 to 1.13)

0.42

67

  Unclear [16]-[18],[20],[23]-[26]

8

899

0.74 (0.62 to 0.89)

0.002

31

  100 [6],[7],[19],[22],[24]-[26]

7

2,192

0.82 (0.70 to 0.95)

0.01

59

  <100 [16]-[18],[20],[21],[23]

6

333

0.81 (0.56 to 1.17)

0.27

61

  ED [6],[7]

2

1,158

0.86 (0.52 to 1.44)

0.52

83

  ICU [16]-[26]

11

1,367

0.81 (0.69 to 0.96)

0.01

53