Diagnosing external ventricular drain-related ventriculitis by means of local inflammatory response: soluble triggering receptor expressed on myeloid cells-1

Table 3 Comparison between different markers in the diagnosis of external ventricular drainage-related ventriculitis

Variable	Ventriculitis	Colonization only	Controls	P
Variable	(number = 6)	(number = 10)	(number = 57)	P
Temperature (°C)	38 (37.35 to 39)	37.8 (37.2 to 38)	37 (36.8 to 38)	0.053
Serum leucocytes (mm³)	15,150 (7,975 to 18,525)	13,900 (10,350 to 14,600)	11,500 (10,000 to 15,650)	0.741
Serum PCT (ng/ml)	0.32 (0.18 to 0.64)	0.17 (0.1 to 0.34)	0.16 (0.10 to 0.37)	0.407
Serum CRP (mg/dl)	122.5 (54.7 to 227)	258 (97 to 294)	52 (22 to 102)	0.018
CSF leucocytes (mm³)	4,480 (2,988 to 4,886)	13.5 (3 to 643)	89 (8.5 to 629.5)	0.007
CSF neutrophils (mm³)	1,200 (707 to 5,288)	16.5 (0 to 993)	102.6 (12 to 610)	0.023
CSF proteins (mg/dl)	500 (341 to 658.5)	23 (19 to 88)	71 (39 to 154)	0.004
CSF glucose (mg/dl)	8 (1 to19.5)	72.5 (59 to 107.5)	76 (61 to 88)	0.001
Ratio CSF/serum glucose	0.083 (0.008 to 0.11)	0.62 (0.57 to 0.67)	0.63 (0.47 to 0.75)	0.001
CSF sTREM-1 (pg/ml)	4,320 (2,987 to 4,886)	162.37 (105 to 406.8)	268 (117.7 to 724)	<0.001

Data expressed as median (interquartile range). CRP, C-reactive protein; CSF, cerebrospinal fluid; PCT, procalcitonin; sTREM-1, soluble triggering receptor expressed on myeloid cells-1.

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