Rotational thromboelastometry predicts thromboembolic complications after major non-cardiac surgery

Table 1 Preoperative rotational thromboelastometry (ROTEM) parameters

ROTEM parameter	Normal values	No thromboembolic complication (n =303), mean (SD)	Thromboembolic complication (n =10), mean (SD)	P-value	AUC ROC
EXTEM
Clotting time, s	42 to 74	55.1 (31.2)	48.7 (16.9)	0.19	---
Clot formation time, s	46 to 148	87.1 (61.7)	58.5 (16.6)	<0.001	0.74
Alpha angle, degrees	63 to 81	74.3 (6.9)	78.4 (3.1)	0.002	0.70
Amplitude at 10/20 minutes, mm	50 to 69	58.2 (8.7)	64.0 (5.4)	0.008	0.72
Maximum clot firmness, mm	49 to 71	65.0 (7.5)	70.4 (5.2)	0.009	0.73
INTEM
Clotting time, s	137 to 246	171.5 (34.1)	165.8 (24.6)	0.11	---
Clot formation time, s	71 to 82	72.2 (57.3)	51.0 (11.4)	<0.001	0.75
Alpha angle, degrees	52 to 72	76.5 (5.5)	79.4 (2.4)	0.006	0.72
Amplitude at 10/20 minutes, mm	137 to 246	56.7 (7.8)	63.0 (5.8)	0.012	0.75
Maximum clot firmness, mm	52 to 72	62.8 (7.1)	68.6 (6.0)	0.02	0.74
FIBTEM
Clotting time, s	43 to 69	53.3 (47.4)	44.7 (13.1)	0.11	---
Clot formation time, s		339.9 (366.5)	378.9 (606.0)	0.12	---
Alpha angle, degrees		73.6 (6.6)	77.0 (5.4)	0.085	---
Amplitude at 10/20 minutes, mm	8 to 21	16.5 (6.8)	23.7 (11.2)	0.010	---
Maximum clot firmness, mm	9 to 25	17.8 (7.6)	24.8 (11.2)	0.015	---

For significant predictive tests, the area under the curve (AUC) of the receiver operating characteristic (ROC) curve is listed. EXTEM, extrinsic rotational thromboelastometry; INTEM, intrinsic rotational thromboelastometry; FIBTEM, fibrinogen rotational thromboelastometry; ns, not significant.

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