Table 1 Comparison of characteristics between the ECPR group and CCPR group
ECPR (n = 55) | CCPR (n = 444) | P-value | |
|---|---|---|---|
Age, years | 53 (41 to 68) | 69 (56 to 77) | <0.001 |
Male : female, n | 41 : 14 | 285 : 159 | 0.136 |
Pre-existing comorbidity, n (%) | |||
Hypertension | 14 (25.5) | 161 (36.3) | 0.134 |
Cardiovascular disease | 15 (27.3) | 101 (22.7) | 0.498 |
Chronic pulmonary disease | 1 (1.8) | 33 (7.4) | 0.157 |
Neurologic disease | 3 (5.5) | 67 (15.1) | 0.062 |
Chronic liver disease | 1 (1.8) | 20 (4.5) | 0.495 |
Chronic kidney disease | 1 (1.8) | 41 (9.2) | 0.070 |
Diabetes | 11 (20.0) | 122 (27.5) | 0.262 |
Malignancy | 1 (1.8) | 38 (8.6) | 0.106 |
Number of pre-existing comorbidities | 0 (0 to 1) | 1 (0 to 2) | 0.003 |
Comorbidity score | 0 (0 to 1) | 1 (0 to 2) | <0.001 |
Witnessed, n (%) | 43 (78.2) | 328 (73.9) | 0.623 |
Bystander CPR, n (%) | 23 (41.8) | 151 (34.0) | 0.294 |
First documented arrest rhythm, n (%) | <0.001 | ||
VF/VT | 31 (56.4) | 85 (19.1) | |
PEA | 10 (18.2) | 91 (20.5) | |
Asystole | 14 (25.5) | 268 (60.4) | |
Arrest to CPR start, minutes | 7 (0 to 13) | 8 (5 to 12) | 0.108 |
CPR duration, minutes | 62 (47 to 89) | 35 (21 to 50) | <0.001 |
Pre-hospital CPR duration | 13 (7 to 17) | 13 (8 to 17) | 0.930 |
In-hospital CPR duration | 47 (35 to 80) | 21 (8 to 35) | <0.001 |
Presumed etiology of arrest, n (%) | <0.001 | ||
Cardiac | 49 (89.1) | 277 (62.4) | |
Non-cardiac | 6 (10.9) | 167 (37.6) | |
At the time of admission to ED | |||
SAPS II* | 91 (87 to 97) | 97 (91 to 103) | <0.001 |
Arterial pH* | 6.98 (6.86 to 7.05) | 6.94 (6.83 to 7.06) | 0.473 |
Serum lactate* | 11.7 (8.8 to 16.0) | 10.8 (7.3 to 14.0) | 0.083 |
Any ROSC events during CPR, n (%) | 17 (30.9) | 94 (21.2) | 0.121 |
Therapeutic hypothermia, n (%) | 17 (30.9) | 71 (16.0) | 0.013 |
ROSB/ROSC, n (%) | 44 (80.0) | 212 (47.7) | <0.001 |
Survival to 24 hours, n (%) | 32 (58.2) | 138 (31.1) | <0.001 |
CPC score at discharge | 0.226 | ||
1, n (%) | 7 (12.1) | 30 (6.8) | |
2, n (%) | 1 (1.8) | 6 (1.4) | |
3, n (%) | 0 (0) | 8 (1.8) | |
4, n (%) | 1 (1.8) | 42 (9.5) | |
5, n (%) | 46 (83.6) | 358 (80.6) | |
Hospital LOS in survival to discharge, day | 30 (14 to 60) | 18 (9 to 30) | 0.120 |
Survivor at 3 months after arrest, n (%) | 8 (14.5) | 44 (9.9) | 0.346 |
CPC 1,2 at 3 months after arrest, n (%) | 8 (14.5) | 36 (8.1) | 0.128 |