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Table 8 Genes upregulated between 20- and 30-fold in peripheral blood mononuclear cells of patients with AECOPD compared to patients with stable COPD a

From: Dynamic gene expressions of peripheral blood mononuclear cells in patients with acute exacerbation of chronic obstructive pulmonary disease: a preliminary study

AE-1 vs stable

AE-3 vs stable

AE-10 vs stable

Fold changes

Genes

Fold changes

Genes

Fold changes

Genes

20.1

MS4A3

20.5

GPR97

20.3

TIMP3

21.0

CEACAM6

20.6

ALPL

20.3

SLC6A4

21.1

SLC25A37

20.7

MTHFS

20.4

SFTPA2

21.2

DCN

21.0

FLJ32028

20.6

AKAP2

22.4

SPP1

21.4

ADM

20.7

DST

24.0

TCN1

23.3

ACSL1

21.2

TCF21

24.7

BPIL1

23.3

DCN

21.5

ADH1C

26.4

SLC25A37

24.3

MMP8

21.6

SLIT3

26.6

CTGF

24.5

TCN1

21.7

C9orf61

28.5

ARG1

25.3

FOS

22.5

FOSB

28.6

FOS

25.3

FOSB

25.5

MFAP4

29.5

SERPINE1

27.5

CTGF

26.0

GPX3

  

28.3

BPIL1

26.5

DCN

  

28.4

VSIG4

26.9

SFTPB

    

27.6

FBLN5

    

28.1

LOC653509

    

28.5

ADH1C

    

28.7

SFTPA1

    

28.7

TIMP3

  1. aData are from patients with patients with acute exacerbation of chronic obstructive pulmonary disease on day 1 (AE-1), day 3 (AE-3) and day 10 (AE-10) of hospital admission, as compared to patients with stable chronic obstructive pulmonary disease (Stable).