Table 16 Genes downregulated more than fivefold in peripheral blood mononuclear cells of patients with AECOPD ^a

5.0

ITGB3

10.2

MPO

10.3

MOXD1

5.1

CGI-69

10.4

LOC653492

10.3

LOC152573

5.2

SPTB

10.5

SPP1

10.7

SPDEF

5.2

BCL2L1

10.6

ANK1

10.8

CCDC80

5.2

GATA1

11.0

DEFA4

11.0

CTSG

5.3

FBXO7

11.0

MOXD1

11.0

CAMP

5.6

SELENBP1

11.0

HIG2

11.3

PLA2G2D

5.8

OSBP2

11.1

OSBP2

11.4

SPP1

5.9

LOC643855

11.2

REXO1L3P

11.6

S100P

6.1

ERAF

11.6

SPDEF

11.7

SLC4A11

6.2

EPB49

12.0

COL1A1

11.8

COL3A1

6.2

MYH9

12.2

BPI

11.8

SPAG4

6.4

ALAS2

12.3

SNCA

12.5

THBS2

7.4

LOC644462

12.3

SLC4A11

12.7

MPO

7.8

GMPR

12.5

COL1A1

13.0

PRTN3

8.1

ANK1

12.6

AZU1

13.2

COL1A1

8.9

BPGM

12.6

ARG1

13.3

ELA2

9.1

FAM46C

13.2

GREM1

14.3

LIF

9.2

LOC643497

13.5

DEFA4

14.4

CEACAM5

9.4

TRIM58

13.5

ELA2

14.6

RNF183

9.4

MBNL3

14.2

CEACAM5

14.9

B3Gn-T6

9.5

EPB49

14.5

ITGA11

15.1

AZU1

9.6

EPB49

15.0

CEACAM8

15.4

ITGA11

9.6

EPB42

15.3

SPTB

15.9

DEFA4

9.7

EPB41

15.6

CEACAM5

16.4

CEACAM5

9.7

SLC14A1

16.6

LIF

17.5

MS4A3

9.9

EPB42

17.1

TRIM58

17.8

ARG1

10.1

SNCA

19.2

THY1

20.4

THY1

13.5

TRIM58

19.5

MS4A3

21.1

MS4A3

19.7

SLC4A1

23.1

TRIM58

22.5

SPP1

20.7

EPB41

24.1

MS4A3

34.4

SFRP2

21.6

CA1

27.1

SFRP2

49.9

PLUNC

29.9

EPB42

57.1

CALCA

30.4

SPP1

68.9

CALCA

41.9

ALAS2

80.4

BPIL1

43.8

EPB42

93.1

BPIL1

44.2

CALCA

48.5

PLUNC

55.5

SLC4A1

58.6

CALCA

70.0

BPIL1

84.3

BPIL1

109.9

CA1