Diagnostic accuracy of delirium diagnosis in pediatric intensive care: a systematic review

Table 2 Methodological quality of the included studies ^a

Study index test	Study flow diagram (Y/N)	QUADAS-2 quality criteria: risk of bias^b				QUADAS-2 quality criteria: applicability concern^b
Study index test	Study flow diagram (Y/N)	Patient selection	Index test	Reference standard	Flow and timing	Patient selection	Index test	Reference standard
PAED [9],[16]	N	High	Unclear	Low	Unclear	Low	Low	Low
p-CAM-ICU [10]	Y	Low	Low	Low	High	High	Low	Low
CAP-D [11]	N	Unclear	Low	Unclear	High	Low	Low	Low
CAP-D(R) [17]	Y	Low	High	Low	Unclear	Low	Low	Low
Clinical suspicion [12]-[15]	N	Low	High	Unclear	High	Low	Low	Low

^aCAP-D, Cornell Assessment of Pediatric Delirium; CAP-D(R), Cornell Assessment of Pediatric Delirium, Revised; PAED, Pediatric Anesthesia Emergence Delirium Scale; p-CAM-ICU, Pediatric Confusion Assessment Method for the Intensive Care Unit; QUADAS-2, Quality Assessment of Diagnostic Accuracy Studies-2; Y/N, Yes or no. ^bA description of the QUADAS-2 criteria for risk of bias and applicability concerns [6] is given in the data collection tool (available as Additional file 2). A low risk of bias indicates better quality compared to high or unclear risk of bias. A low applicability concern indicates better quality compared to high or unclear applicability concern.

ISSN: 1364-8535