Skip to main content

Table 3 Variables associated with delayed cerebral ischemia and functional outcome in 46 subarachnoid hemorrhage patients with Takotsubo cardiomyopathy on multivariate analysis a

From: Impact of transpulmonary thermodilution-based cardiac contractility and extravascular lung water measurements on clinical outcome of patients with Takotsubo cardiomyopathy after subarachnoid hemorrhage: a retrospective observational study

Covariates Odds ratio (95% confidence interval) P-value
DCI   
 WFNS grade IV or V 1.64 (0.07 – 5.87) 0.70
 Duration of low CFI, days 2.14 (1.33 – 2.84) 0.004*
 Coexist pulmonary edema (ELWI >14 ml/kg) after day 4 1.66 (0.32 – 2.21) 0.36
Poor functional outcome at 3-month follow-up   
 WFNS grade IV or V 1.17 (0.46 – 3.76) 0.20
 DCI 1.68 (0.07 – 7.29) 0.39
 Duration of low CFI, days 1.87 (1.06 – 3.29) 0.02*
 Pulmonary edema after day 4 2.10 (1.11 – 3.97) 0.04*
 Length of ICU stay, days 1.93 (0.54 – 1.41) 0.59
  1. aCFI: Cardiac function index; DCI: Delayed cerebral ischemia; ELWI: Extravascular lung water index; WFNS: World Federation of Neurological Surgeons. Poor functional outcome was defined as modified Rankin Scale scores of 4 to 6. Pulmonary edema was defined as ELWI >14 ml/kg based on the PiCCO™ measurements. Duration of low CFI was defined by at least one CFI <4.2 min−1 (corresponding to predicted LVEF <40%) over 24 hours. *Significant P-values.