Figure 3

Changes in cardiac function index during volume expansion and hyperdynamic therapy for delayed cerebral ischemia–related neurological deterioration in 25 subarachnoid hemorrhage patients with Takotsubo cardiomyopathy. Graph shows changes in cardiac index (CI), global end-diastolic volume index (GEDI) and cardiac function index (CFI) during volume expansion with 500 ml of 6% hydroxyethyl starch (HES) (n = 112) or hyperdynamic therapy with dobutamine (DOB) (n = 55). Data were collected before and after each challenge (a 500 ml infusion of HES or an incremental infusion (3 μg/kg/min) of DOB, sampled in situations without coadministration) between days 4 and 14. *P < 0.05, **P < 0.01 compared with baseline before each challenge (% change).