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Table 3 Summary of the cumulative mortality rate at days 7, 30, and 90 in patients admitted to the ICU from 2005 to 2010 according to the presence of severe sepsis

From: Mortality of patients infected with HIV in the intensive care unit (2005 through 2010): significant role of chronic hepatitis C and severe sepsis

 

3a: Non-HIV versus all-HIV patients

3b: HIV versus HIV/HCV patients

Control group

All HIV group

P value (a)

HIV group

HIV/HCV group

P value (b)

(No. = 7,496)

(No. = 1,891)

(No. = 1.191)

(No. = 700)

Day 7

Number of deaths (*)

2,162

690

 

363

327

 
 

Cumulative mortality rate (**)

      
 

All patients

28.8 (27.6; 30.1)

36.5 (33.8; 39.2)

<0.001

30.5 (27.3; 33.6)

46.7 (41.6; 51.8)

<0.001

 

Patients with severe sepsis

26.1 (24.3; 27.9)

35.3 (31.7; 38.7)

<0.001

29.2 (25.4; 33.2)

46.5 (39.6; 53.3)

<0.001

 

Patients without severe sepsis

30.6 (28.9; 32.2)

38.2 (33.9; 42.5)

<0.001

32.3 (27.2; 37.4)

47.1 (39.5; 54.5)

<0.001

 

P value (c)

<0.001

0.210

 

0.292

0.941

 

Day 30

Number of deaths (*)

3819

1285

 

765

520

 
 

Cumulative mortality rate (**)

      
 

All patients

50.9 (49.3; 52.5)

67.9 (64.2; 71.7)

<0.001

64.2 (59.7; 68.8)

74.3 (67.9; 80.7)

<0.001

 

Patients with severe sepsis

64.0 (61.1; 66.9)

73.8 (68.7; 78.9)

<0.001

69.5 (63.3; 75.6)

81.9 (72.8; 90.9)

<0.001

 

Patients without severe sepsis

42.4 (40.5; 44.3)

59.9 (54.6; 65.3)

<0.001

56.4 (49.7; 63.2)

65.2 (56.3; 74.1)

0.016

 

P value (c)

<0.001

<0.001

 

<0.001

<0.001

 

Day 90

Number of deaths (*)

4419

1531

 

958

573

 
 

Cumulative mortality rate (**)

      
 

All patients

58.9 (57.2; 60.7)

80.9 (76.9; 85.1)

<0.001

80.4 (75.3; 85.5)

81.9 (75.1; 88.6)

0.484

 

Patients with severe sepsis

80.6 (77.3; 83.8)

90.7 (85.1; 96.4)

<0.001

90.7 (83.7; 97.7)

90.8 (81.2; 99.9)

0.999

 

Patients without severe sepsis

44.9 (42.9; 46.8)

67.6 (61.8; 73.3)

<0.001

65.2 (57.9; 72.4)

71.2 (61.9; 80.4)

0.092

 

P value (c)

<0.001

<0.001

 

<0.001

<0.001

 
  1. Values were expressed as follow: (*)absolute count; (**)percentage and 95% confidence interval (95% CI).
  2. P-values were calculated by χ2 test: (a)differences between control group and all HIV group; (b)differences between HIV-group and HIV/HCV group; (c)differences between severe sepsis and other causes. P-values in bold indicates statistically significant differences between groups. HCV, hepatitis C virus; HIV, human immunodeficiency virus.