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Table 3 Summary of the cumulative mortality rate at days 7, 30, and 90 in patients admitted to the ICU from 2005 to 2010 according to the presence of severe sepsis

From: Mortality of patients infected with HIV in the intensive care unit (2005 through 2010): significant role of chronic hepatitis C and severe sepsis

  3a: Non-HIV versus all-HIV patients 3b: HIV versus HIV/HCV patients
Control group All HIV group P value (a) HIV group HIV/HCV group P value (b)
(No. = 7,496) (No. = 1,891) (No. = 1.191) (No. = 700)
Day 7 Number of deaths (*) 2,162 690   363 327  
  Cumulative mortality rate (**)       
  All patients 28.8 (27.6; 30.1) 36.5 (33.8; 39.2) <0.001 30.5 (27.3; 33.6) 46.7 (41.6; 51.8) <0.001
  Patients with severe sepsis 26.1 (24.3; 27.9) 35.3 (31.7; 38.7) <0.001 29.2 (25.4; 33.2) 46.5 (39.6; 53.3) <0.001
  Patients without severe sepsis 30.6 (28.9; 32.2) 38.2 (33.9; 42.5) <0.001 32.3 (27.2; 37.4) 47.1 (39.5; 54.5) <0.001
  P value (c) <0.001 0.210   0.292 0.941  
Day 30 Number of deaths (*) 3819 1285   765 520  
  Cumulative mortality rate (**)       
  All patients 50.9 (49.3; 52.5) 67.9 (64.2; 71.7) <0.001 64.2 (59.7; 68.8) 74.3 (67.9; 80.7) <0.001
  Patients with severe sepsis 64.0 (61.1; 66.9) 73.8 (68.7; 78.9) <0.001 69.5 (63.3; 75.6) 81.9 (72.8; 90.9) <0.001
  Patients without severe sepsis 42.4 (40.5; 44.3) 59.9 (54.6; 65.3) <0.001 56.4 (49.7; 63.2) 65.2 (56.3; 74.1) 0.016
  P value (c) <0.001 <0.001   <0.001 <0.001  
Day 90 Number of deaths (*) 4419 1531   958 573  
  Cumulative mortality rate (**)       
  All patients 58.9 (57.2; 60.7) 80.9 (76.9; 85.1) <0.001 80.4 (75.3; 85.5) 81.9 (75.1; 88.6) 0.484
  Patients with severe sepsis 80.6 (77.3; 83.8) 90.7 (85.1; 96.4) <0.001 90.7 (83.7; 97.7) 90.8 (81.2; 99.9) 0.999
  Patients without severe sepsis 44.9 (42.9; 46.8) 67.6 (61.8; 73.3) <0.001 65.2 (57.9; 72.4) 71.2 (61.9; 80.4) 0.092
  P value (c) <0.001 <0.001   <0.001 <0.001  
  1. Values were expressed as follow: (*)absolute count; (**)percentage and 95% confidence interval (95% CI).
  2. P-values were calculated by χ2 test: (a)differences between control group and all HIV group; (b)differences between HIV-group and HIV/HCV group; (c)differences between severe sepsis and other causes. P-values in bold indicates statistically significant differences between groups. HCV, hepatitis C virus; HIV, human immunodeficiency virus.