3a: Non-HIV versus all-HIV patients | 3b: HIV versus HIV/HCV patients | ||||||
---|---|---|---|---|---|---|---|
Control group | All HIV group | P value (a) | HIV group | HIV/HCV group | P value (b) | ||
(No. = 7,496) | (No. = 1,891) | (No. = 1.191) | (No. = 700) | ||||
Day 7 | Number of deaths (*) | 2,162 | 690 | 363 | 327 | ||
Cumulative mortality rate (**) | |||||||
All patients | 28.8 (27.6; 30.1) | 36.5 (33.8; 39.2) | <0.001 | 30.5 (27.3; 33.6) | 46.7 (41.6; 51.8) | <0.001 | |
Patients with severe sepsis | 26.1 (24.3; 27.9) | 35.3 (31.7; 38.7) | <0.001 | 29.2 (25.4; 33.2) | 46.5 (39.6; 53.3) | <0.001 | |
Patients without severe sepsis | 30.6 (28.9; 32.2) | 38.2 (33.9; 42.5) | <0.001 | 32.3 (27.2; 37.4) | 47.1 (39.5; 54.5) | <0.001 | |
P value (c) | <0.001 | 0.210 | 0.292 | 0.941 | |||
Day 30 | Number of deaths (*) | 3819 | 1285 | 765 | 520 | ||
Cumulative mortality rate (**) | |||||||
All patients | 50.9 (49.3; 52.5) | 67.9 (64.2; 71.7) | <0.001 | 64.2 (59.7; 68.8) | 74.3 (67.9; 80.7) | <0.001 | |
Patients with severe sepsis | 64.0 (61.1; 66.9) | 73.8 (68.7; 78.9) | <0.001 | 69.5 (63.3; 75.6) | 81.9 (72.8; 90.9) | <0.001 | |
Patients without severe sepsis | 42.4 (40.5; 44.3) | 59.9 (54.6; 65.3) | <0.001 | 56.4 (49.7; 63.2) | 65.2 (56.3; 74.1) | 0.016 | |
P value (c) | <0.001 | <0.001 | <0.001 | <0.001 | |||
Day 90 | Number of deaths (*) | 4419 | 1531 | 958 | 573 | ||
Cumulative mortality rate (**) | |||||||
All patients | 58.9 (57.2; 60.7) | 80.9 (76.9; 85.1) | <0.001 | 80.4 (75.3; 85.5) | 81.9 (75.1; 88.6) | 0.484 | |
Patients with severe sepsis | 80.6 (77.3; 83.8) | 90.7 (85.1; 96.4) | <0.001 | 90.7 (83.7; 97.7) | 90.8 (81.2; 99.9) | 0.999 | |
Patients without severe sepsis | 44.9 (42.9; 46.8) | 67.6 (61.8; 73.3) | <0.001 | 65.2 (57.9; 72.4) | 71.2 (61.9; 80.4) | 0.092 | |
P value (c) | <0.001 | <0.001 | <0.001 | <0.001 |