| Â | ALIp | ALIexp |
|---|
| Â | PCV | PSV | PCV | PSV |
|---|
| Â | NS | Sigh | NS | Sigh | NS | Sigh | NS | Sigh |
|---|
Lung | 2 (2-3) | 2 (2-3) | 2 (1-2) | 2 (1.5-2) | 1 (1-2) | 3 (2-3)* | 1 (1-1.25) | 2 (2-2.25) |
Liver | 1 (1-1.5) | 1 (1-1.5) | 2 (1-2) | 1 (1-2) | 2 (2-3) | 2 (2-3) | 2 (2-2.25) | 2 (2-3) |
Kidney | 1 (1-2) | 2 (1-2) | 1 (1-1.5) | 1 (1-2) | 3 (2-3) | 2 (2-3) | 2 (2-2.25) | 3 (2-3) |
- Values expressed as median (interquartile range) of five animals in each group. A five-point, semiquantitative, severity-based scoring system was used. Pathological findings were graded as: 0 = normal lung parenchyma; 1 = changes in 1 to 25%; 2 = changes in 26 to 50%; 3 = changes in 51 to 75%; and 4 = changes in 76 to 100% of examined tissue. *Significantly different from PCV-NS (P <0.05). ALIp, pulmonary acute lung injury; ALIexp, extrapulmonary acute lung injury; PCV, pressure-controlled ventilation; PSV, pressure support ventilation; NS, non-sigh.
